P4154
Polyinosinic acid potassium salt
Homopolymer
Synonym(s):
Poly(I) potassium salt
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About This Item
Pricing and availability is not currently available.
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biological source
synthetic (organic)
Quality Level
Assay
≥98% (TLC)
form
lyophilized powder
solubility
water: 4.80-5.20 mg/mL, clear to hazy, colorless to faintly yellow
storage temp.
−20°C
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Application
Polyinosinic acid (Poly(I)) is a homopolymer of inosine that may be used with polycytidylic acid (poly(C)) to form the double-stranded homopolymer (Poly(I) • Poly(C)). TLR3 recognizes double-stranded RNA and is a major effector of the immune response against viral pathogens. (Poly(I) • Poly(C)) is a used as a model RNA to study cell signaling at the level of TLR3. Poly(IC) is a TRIF-dependent toll-like receptor-3 (TLR3) ligand.
Preparation Note
Prepared from IDP using polynucleotide phosphorylase.
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
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