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G2752

Sigma-Aldrich

Gly-Phe

≥97.0% (TLC)

Synonym(s):

Glycyl-L-phenylalanine

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About This Item

Linear Formula:
NH2CH2CONHCH(COOH)CH2C6H5
CAS Number:
3321-03-7
Molecular Weight:
222.24
Beilstein:
2279318
EC Number:
222-027-9
MDL number:
MFCD00065110
UNSPSC Code:
12352209
PubChem Substance ID:
24895100
NACRES:
NA.26

product name

Gly-Phe,

Assay

≥97.0% (TLC)

form

crystalline

color

white

mp

264 °C

storage temp.

−20°C

SMILES string

NCC(=O)N[C@@H](Cc1ccccc1)C(O)=O

InChI

1S/C11H14N2O3/c12-7-10(14)13-9(11(15)16)6-8-4-2-1-3-5-8/h1-5,9H,6-7,12H2,(H,13,14)(H,15,16)/t9-/m0/s1

InChI key

JBCLFWXMTIKCCB-VIFPVBQESA-N

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Related Categories

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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S J Reshkin et al.
The American journal of physiology, 260(3 Pt 2), R563-R569 (1991-03-01)
The transport mechanisms for the dipeptide glycyl-L-phenylalanine (Gly-Phe) and L-phenylalanine (Phe) were characterized in fish intestinal brush-border membrane vesicles (BBMV). Gly-Phe was rapidly hydrolyzed only intravesicularly with almost total hydrolysis occurring even at 10 s. Dipeptide uptake was not stimulated
Resolution of chiral compounds by HPLC using mobile phase additives and a porous graphitic carbon stationary phase.
B J Clark et al.
Journal of pharmaceutical and biomedical analysis, 7(12), 1883-1888 (1989-01-01)
T Takarada et al.
Chemistry (Weinheim an der Bergstrasse, Germany), 6(21), 3906-3913 (2000-12-29)
Oligopeptides are efficiently hydrolyzed by Ce(IV) to the corresponding amino acids under mild conditions. The pseudo first-order rate constants for the hydrolysis of H-Gly-Phe-OH and H-Gly-Gly-OH at pH 7.0 and 50 degrees C are 3.5 x 10(-1) and 2.8 x
Roderick Y H Lim et al.
Proceedings of the National Academy of Sciences of the United States of America, 103(25), 9512-9517 (2006-06-14)
Natively unfolded phenylalanine-glycine (FG)-repeat domains are alleged to form the physical constituents of the selective barrier-gate in nuclear pore complexes during nucleocytoplasmic transport. Presently, the biophysical mechanism behind the selective gate remains speculative because of a lack of information regarding
Susan Weng Larsen et al.
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences, 22(5), 399-408 (2004-07-22)
Oil-based depot formulations may constitute a future delivery method for small peptides. Thus, a requirement is attainment of sufficient oil solubility for such active compounds. A model dipeptide (Gly-Phe) has been converted into lipophilic prodrugs by esterification at the C-terminal
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