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G0262

Sigma-Aldrich

Gelatin hydrolysate Enzymatic

Synonym(s):

Peptone from gelatin

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About This Item

CAS Number:
EC Number:
MDL number:
UNSPSC Code:
12352202
NACRES:
NA.61
Pricing and availability is not currently available.

biological source

Porcine

Quality Level

form

powder

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General description

Gelatin hydrolysate is extracted from pigs, bovines, and fish by the hydrolysis of gelatin.

Application

Gelatin hydrolysate Enzymatic has been used :
  • in immunoassay[1]
  • as an excipient in vaccine formulation to screen its ability to stabilize influenza vaccine[2]
  • for the synthesis of gelatin hydrolysate vinyl esters[3]

Biochem/physiol Actions

Gelatin hydrolysate possesses antioxidant, angiotensin-converting enzyme (ACE)-inhibitory, antifreeze, and antiphotoaging activities. It is widely used in the food and pharmaceutical industries. Gelatin hydrolysate is used as a smart drug delivery carrier for cancer therapy and in wound dressing. It boosts skin recovery by supporting wound closure and diminishing skin wrinkles. When orally consumed, gelatin hydrolysates increase bone mass and inhibit osteopenia.[4]

Storage Class Code

11 - Combustible Solids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Min-Hsuan Lin et al.
Microbiology spectrum, 10(6), e0394922-e0394922 (2022-11-30)
More than 100 arboviruses, almost all of which have an RNA genome, cause disease in humans. RNA viruses are causing unprecedented health system challenges worldwide, many with little or no specific therapies or vaccines available. Certain species of mosquito can
Hydrolysis Process Optimization and Functional Characterization of Yak Skin Gelatin Hydrolysates
Yang H, et al.
Journal of Chemistry (2019)
F Elsaesser
Neuroendocrinology, 74(5), 288-299 (2001-11-06)
It has repeatedly been suggested that galanin acts within the anterior pituitary (AP) in an auto/paracrine manner to modulate luteinizing hormone (LH) release. Except for one recent report in the rat, evidence for this notion is absent. The purpose of
Induction of cross clade reactive specific antibodies in mice by conjugates of HGP-30 (peptide analog of HIV-1SF2 p17) and peptide segments of human beta-2-microglobulin or MHC II beta chain
Zimmerman DH, et al.
Vaccine, 19(32), 4750-4759 (2001)
Three-dimensional microfabrication of protein hydrogels via two-photon-excited thiol-vinyl ester photopolymerization
Qin XH, et al.
Journal of Polymer Science Part A: Polymer Chemistry, 51(22), 4799-4810 (2013)

Questions

1–2 of 2 Questions  
  1. Is this product a gelatin hydrolyzed using enzymes? Is there a freeze-drying or drying process during the product manufacturing process? May I know under what conditions it was hydrolyzed?(Conditions such as temperature and time)

    1 answer
    1. Yes, as noted in the product name, this item is an enzymatic digest. This pancreatic digestion results in the hydrolysis of the peptide bonds of the gelatin proteins, as mentioned in the 'DESCRIPTION' section. Unfortunately, the conditions and preparation method for this material are considered proprietary.

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  2. what is the molecular weight of gelatin hydrolysate enzymatic manufactured by sigma?

    1 answer
    1. This product is a pancreatic digest of porcine gelatin. The molecular weights of the resulting gelatin fragments have not been determined. However, the predicted range is 1000 - 5000 daltons with an expected average of 1900 - 2000 daltons.

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