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C2278

Sigma-Aldrich

CAPSO

≥99% anhydrous basis (titration)

Synonym(s):

3-(Cyclohexylamino)-2-hydroxy-1-propanesulfonic acid, CAPSO Free Acid

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About This Item

Empirical Formula (Hill Notation):
C9H19NO4S
CAS Number:
73463-39-5
Molecular Weight:
237.32
Beilstein:
5939234
MDL number:
MFCD00041778
UNSPSC Code:
12161700
PubChem Substance ID:
24892483
NACRES:
NA.25
Pricing and availability is not currently available.

Assay

≥99% anhydrous basis (titration)

form

crystalline powder

pH

2.5-4.0

useful pH range

8.9-10.3

pKa (25 °C)

9.6

solubility

water: 0.111 g/mL, clear, colorless

application(s)

diagnostic assay manufacturing

SMILES string

OC(CNC1CCCCC1)CS(O)(=O)=O

InChI

1S/C9H19NO4S/c11-9(7-15(12,13)14)6-10-8-4-2-1-3-5-8/h8-11H,1-7H2,(H,12,13,14)

InChI key

INEWUCPYEUEQTN-UHFFFAOYSA-N

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General description

CAPSO is a useful secondary standard buffer. Second dissociation constant pK2 value of CAPSO has been measured.[1] Useful pH range for CAPSO is 8.9 - 10.3.

Application

CAPSO was used as biological buffer in the following studies:
  • To maintain pH 9 during water leach test for the analysis of high-carbon coal fly ash-soil mixtures.[2]
  • Chemiluminescent in situ hybridization using soybean peroxidase-labeled peptide nucleic acid (PNA) probes.[3] I
  • Preparation of planar bilayer lipid membranes.[4]
It may be employed as buffer for the electrophoretic analyses in non-denaturing gels, to investigate macromolecular self-association of ADP-ribosyltransferase protein in solution.[5]

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Certificates of Analysis (COA)

Lot/Batch Number
0000344973
0000344973
SLCQ3729
SLCQ3732
SLCQ3730

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MOPS ≥99.5% (titration)

Sigma-Aldrich

M1254

MOPS

3-(Cyclohexylamino)-1-propanesulphonic acid for synthesis

Sigma-Aldrich

8.43280

3-(Cyclohexylamino)-1-propanesulphonic acid

Second dissociation constants of 3-(cyclohexylamino)-1-propanesulfonic acid (CAPS) and 3-(cyclohexylamino)-2-hydroxy-1-propanesulfonic acid (CAPSO) from the temperatures 278.15 K to 328.15 K.
Roy RN, et al.
The Journal of Chemical Thermodynamics, 29(7), 749-756 (1997)
P I Bauer et al.
The Biochemical journal, 270(1), 17-26 (1990-08-15)
The macromolecular self-association of ADP-ribosyltransferase protein in solution was studied by several experimental techniques: quantitative gel filtration, electrophoretic analyses in non-denaturing gels, and cross-linking the enzyme protein with glutaraldehyde, dimethyl pimelimidate, dimethyl suberimidate, dimethyl 3,3'-dithiobisproprionimidate and tetranitromethane. The self-association of
H Stender et al.
Applied and environmental microbiology, 67(1), 142-147 (2001-01-03)
A new chemiluminescent in situ hybridization (CISH) method provides simultaneous detection, identification, and enumeration of culturable Escherichia coli cells in 100 ml of municipal water within one working day. Following filtration and 5 h of growth on tryptic soy agar
Andreas Missner et al.
The Journal of biological chemistry, 283(37), 25340-25347 (2008-07-12)
Several membrane channels, like aquaporin-1 (AQP1) and the RhAG protein of the rhesus complex, were hypothesized to be of physiological relevance for CO(2) transport. However, the underlying assumption that the lipid matrix imposes a significant barrier to CO(2) diffusion was
Evaluation of leaching protocols for testing of high-carbon coal fly ash-soil mixtures.
Becker J, et al.
Journal of Environmental Engineering (New York, N.Y.), 139(5), 642-653 (2012)
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Questions

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  1. How can I determine the shelf life / expiration / retest date of this product?

    1 answer

    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/449/386/product-dating-information-mk.pdf

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  2. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 answer

    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

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  3. Hallo, ich würde Ablaufdatum brauchen? Danke

    1 answer

    1. This product does not contain an expiration date or recommended retest date. Products with no expiration date or recommended retest date should be routinely inspected by customers to ensure they perform as expected. These products are also subject to a one year warranty from the date of shipment. For more information you may access the "Product Dating Information" document under "ADDITIONAL USEFUL DOCUMENTS ABOUT OUR PRODUCTS" at the bottom of the Quality Services page with this link: https://www.sigmaaldrich.com/US/en/life-science/quality-and-regulatory-management/quality-services

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