The product is a neat liquid,
Predicted density is 0.882 +/- 0.06 g/cm3 at a temperature of 20°C and a pressure of 760 Torr. Based on this density and the product's molecular weight of 426.7 g/mol, its molar concentration is calculated to be approximately 2.07 mol/liter.
41043
2,3-Oxidosqualene
≥92.0% (HPLC)
Synonym(s):
2,3-Epoxy-2,3-dihydrosqualene, 22,23-Epoxy-2,6,10,15,19,23-hexamethyl-2,6,10,14,18-tetracosapentaene, Squalene 2,3-epoxide, Squalene 2,3-oxide
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All Photos(4)
About This Item
CAS Number:
MDL number:
UNSPSC Code:
12352202
PubChem Substance ID:
NACRES:
NA.32
Pricing and availability is not currently available.
Recommended Products
Quality Level
Assay
≥92.0% (HPLC)
storage temp.
−20°C
SMILES string
C\C(C)=C\CC\C(C)=C\CC\C(C)=C\CC\C=C(/C)CC\C=C(/C)CCC1OC1(C)C
InChI
1S/C30H50O/c1-24(2)14-11-17-27(5)20-12-18-25(3)15-9-10-16-26(4)19-13-21-28(6)22-23-29-30(7,8)31-29/h14-16,20-21,29H,9-13,17-19,22-23H2,1-8H3/b25-15+,26-16+,27-20+,28-21+
InChI key
QYIMSPSDBYKPPY-BANQPHDMSA-N
Related Categories
Application
- Lanosterol synthase deficiency promotes tumor progression by orchestrating PDL1-dependent tumor immunosuppressive microenvironment.: Demonstrates how lanosterol synthase, linked to 2,3-Oxidosqualene, influences tumor environments, potentially informing cancer treatment strategies (Gao et al., 2024).
- Promiscuous Oxidosqualene Cyclases from Neoalsomitra integrifoliola Catalyzing the Formation of Tetracyclic, Pentacyclic, and Heterocyclic Triterpenes.: Investigates the versatility of oxidosqualene cyclases, which could have implications for synthetic applications of 2,3-Oxidosqualene in producing diverse triterpenes (Li et al., 2024).
Biochem/physiol Actions
2,3-Oxidosqualene is a substrate of the 2,3-oxidosqualene cyclase lanosterol synthase. 2,3-oxidosqualene cyclase has been shown to be suppressed by a high fat diet and high levels of cholesterol. [1]
Packaging
Bottomless glass bottle. Contents are inside inserted fused cone.
Storage Class Code
10 - Combustible liquids
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
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Huaixin Dang et al.
The Journal of biological chemistry, 284(10), 6218-6226 (2009-01-03)
The liver X receptors (LXRs) sense oxysterols and regulate genes involved in cholesterol metabolism. Synthetic agonists of LXRs are potent stimulators of fatty acid synthesis, which is mediated largely by sterol regulatory element-binding protein-1c (SREBP-1c). Paradoxically, an improved hepatic lipid
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