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Y0002042

Etanercept BRP

European Pharmacopoeia (EP) Reference Standard

Synonym(s):

Etanercept

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About This Item

CAS Number:
185243-69-0
UNSPSC Code:
41116107
NACRES:
NA.24
Pricing and availability is not currently available.

grade

pharmaceutical primary standard

API family

etanercept

manufacturer/tradename

EDQM

application(s)

pharmaceutical

format

neat

storage temp.

−20°C

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General description

Etanercept is a tumor necrosis factor (TNF) antagonist that acts by binding with TNF cytokine or protein, thereby blocking its interaction with cell surface receptors. This dimeric fusion protein consists of 934 amino acids with a molecular mass of ~150KDa.[1][2]
This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the Issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.

Application

This European Pharmacopoeia reference standard is intended for use only as specifically prescribed in the European Pharmacopoeia.

Packaging

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Other Notes

Sales restrictions may apply.

related product

Product No.
Description
Pricing

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

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Certificates of Analysis (COA)

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Questions

1–3 of 3 Questions  

  1. How much is in this item? There's no mg/IU listed on the website.

    1 answer

    1. The BRP consists of freeze-dried Etanercept and is presented in an ampoule with an assigned potency of 10,000 IU/ampoule.

      Helpful?

  2. Shall I inject the Etanercept (Y0001969) reconstituted with water to animals within 6 hours? Can I store the reconstituted Etanercept powder (Y0001969) in 2-8C for up to 14 days?

    1 answer

    1. This is a product of the European Pharmacopoeia. The material is not intended for use in humans or animals. The item is a Reference Standard intended for analytical use in applications such as HPLC or GC. It is recommended to store the solution in working aliquots at -20°C for up to 1 month. Avoid repeated freeze/thaw cycles.

      Helpful?

  3. I would like to ask what is the difference between Etanercept BRP (Y0002042) and Etanercept (Y0001969)?

    1 answer

    1. Product Y0001969 is Etanercept CRS (Certified Reference Standard). Each vial contains approximately 25 mg. The exact **mass** is reported on the EDQM leaflet.

      Please access the leaflet in the link below:
      https://crs.edqm.eu/db/4DCGI/View=Y0001969
      .
      Product Y0002042 is Etanercept BRP (Biological Reference Preparation). Each vial contains approximately 50 mg. The exact **potency** is reported on the EDQM leaflet.

      Please access the leaflet in the link below:
      https://crs.edqm.eu/db/4DCGI/View=Y0002042

      Helpful?

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