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Y0000882

Adrenaline

European Pharmacopoeia (EP) Reference Standard

Synonym(s):

(−)-Epinephrine, (−)-Adrenalin, (R)-(−)-3,4-Dihydroxy-α-(methylaminomethyl)benzyl alcohol, L-Adrenaline, L-Epinephrine

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About This Item

Linear Formula:
(HO)2C6H3CH(OH)CH2NHCH3
CAS Number:
51-43-4
Molecular Weight:
183.20
Beilstein:
2368277
MDL number:
MFCD00002204
UNSPSC Code:
41116107
PubChem Substance ID:
329831202
NACRES:
NA.24

grade

pharmaceutical primary standard

API family

adrenaline

manufacturer/tradename

EDQM

mp

215 °C (dec.) (lit.)

application(s)

pharmaceutical (small molecule)

format

neat

storage temp.

2-8°C

SMILES string

CNC[C@H](O)c1ccc(O)c(O)c1

InChI

1S/C9H13NO3/c1-10-5-9(13)6-2-3-7(11)8(12)4-6/h2-4,9-13H,5H2,1H3/t9-/m0/s1

InChI key

UCTWMZQNUQWSLP-VIFPVBQESA-N

Gene Information

human ... ADRA1A(148) , ADRA1B(147) , ADRA1D(146) , ADRA2A(150) , ADRA2B(151) , ADRA2C(152) , ADRB1(153) , ADRB2(154) , ADRB3(155)

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General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the Issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Adrenaline EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

Biochem/physiol Actions

Adrenoceptor agonist.

Packaging

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Other Notes

Sales restrictions may apply.

related product

Product No.
Description
Pricing

A0300000

Adrenaline tartrate, European Pharmacopoeia (EP) Reference Standard

Y0000740

Adrenaline impurity mixture, European Pharmacopoeia (EP) Reference Standard

Y0000707

Adrenaline tartrate with impurity A, European Pharmacopoeia (EP) Reference Standard

Y0000883

Adrenaline with impurity F, European Pharmacopoeia (EP) Reference Standard

1011878

Adrenalone hydrochloride, United States Pharmacopeia (USP) Reference Standard

BP003

Adrenaline acid tartrate, British Pharmacopoeia (BP) Reference Standard

PHR2478

Adrenalone hydrochloride, Pharmaceutical Secondary Standard; Certified Reference Material

Y0002246

Adrenaline impurity F, CRS, European Pharmacopoeia (EP) Reference Standard

Pictograms

Skull and crossbones
GHS06

Signal Word

Danger

Hazard Statements

H301 + H331,H310

Hazard Classifications

Acute Tox. 2 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral

Storage Class Code

6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

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Mark M Kushnir et al.
Clinical chemistry, 52(8), 1559-1567 (2006-06-17)
Congenital adrenal hyperplasia is a group of autosomal recessive disorders caused by a deficiency of 1 of 4 enzymes required for the synthesis of glucocorticoids, mineralocorticoids, and sex hormones. Analysis of 11-deoxycortisol (11DC), 17-hydroxyprogesterone (17OHP), 17-hydroxypregnenolone (17OHPr), and pregnenolone (Pr)
Jonathan D Jacobs et al.
Pediatrics, 133(1), e8-13 (2013-12-18)
Research suggests that hypertonic saline (HS) may improve mucous flow in infants with acute bronchiolitis. Data suggest a trend favoring reduced length of hospital stay and improved pulmonary scores with increasing concentration of nebulized solution to 3% and 5% saline
Michael B Levy et al.
Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology, 112(1), 58-63 (2013-12-18)
Avoidance strategies in patients with cow's milk allergy occasionally fail to protect these patients from inadvertent exposures, leading to life-threatening reactions. To assess the safety and efficacy of milk oral immunotherapy as an alternative therapeutic strategy. Patients (n = 280
Candice Bjornson et al.
The Cochrane database of systematic reviews, (2)(2), CD006619-CD006619 (2011-02-18)
Croup is a common childhood illness characterized by barky cough, stridor, hoarseness and respiratory distress. Children with severe croup are at risk for intubation. Nebulized epinephrine (NE) may prevent intubation. To evaluate the efficacy and safety of NE in children
Lisa Hartling et al.
The Cochrane database of systematic reviews, (6)(6), CD003123-CD003123 (2011-06-17)
Bronchodilators are commonly used for acute bronchiolitis, despite uncertain effectiveness. To examine the efficacy and safety of epinephrine in children less than two with acute viral bronchiolitis. We searched CENTRAL (2010, Issue 3) which contains the Acute Respiratory Infections Group's
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