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H9645

Supelco

p-Hydroxymethamphetamine

analytical standard, for drug analysis

Synonym(s):

Pholderin

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About This Item

Empirical Formula (Hill Notation):
C10H15NO
CAS Number:
370-14-9
Molecular Weight:
165.23
EC Number:
206-725-0
MDL number:
MFCD00178702
UNSPSC Code:
41116107
PubChem Substance ID:
329815268
NACRES:
NA.24

grade

analytical standard, for drug analysis

Quality Level

200

Assay

≥98% (TLC)

drug control

Home Office Schedule 1; regulated under CDSA - not available from Sigma-Aldrich Canada

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

application(s)

forensics and toxicology
pharmaceutical (small molecule)
veterinary

format

neat

storage temp.

−20°C

SMILES string

CNC(C)Cc1ccc(O)cc1

InChI

1S/C10H15NO/c1-8(11-2)7-9-3-5-10(12)6-4-9/h3-6,8,11-12H,7H2,1-2H3

InChI key

SBUQZKJEOOQSBV-UHFFFAOYSA-N

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Application

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Biochem/physiol Actions

A metabolite of methamphetamine; sympathomimetic

Pictograms

Exclamation mark
GHS07

Signal Word

Warning

Hazard Statements

H315,H319,H335

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Target Organs

Respiratory system

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Certificates of Analysis (COA)

Lot/Batch Number
13100905
037M4150V
016M4036V
095M4039V

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Shimosato, K., et al.
Journal of Chromatographic Science, 377, 279-279 (1986)
T Yamamoto et al.
Journal of analytical toxicology, 13(2), 117-119 (1989-03-01)
A sensitive and specific gas chromatography/mass spectrometry (GC/MS) method has been developed for the simultaneous analysis of methampthetamine and its metabolites (amphetamine, p-hydroxymethamphetamine, and p-hydroxyamphetamine) in monkey urine. The method has been applied to the analysis of urine samples from
N Shima et al.
Xenobiotica; the fate of foreign compounds in biological systems, 36(2-3), 259-267 (2006-05-17)
The urinary concentrations of the main metabolites of methamphetamine (MA), specifically p-hydroxymethamphetamine-sulfate (p-OHMA-Sul) and p-hydroxymethamphetamine-glucuronide (p-OHMA-Glu), were directly measured in MA users and rats using an optimized LC-ESI MS method. The concentrations of the two conjugates in 50 MA human
O Al-Dirbashi et al.
Journal of chromatography. B, Biomedical sciences and applications, 712(1-2), 105-112 (1998-08-11)
A simple, rapid and highly sensitive high-performance liquid chromatographic method for the determination of methamphetamine and its metabolites in human urine was developed. Without tedious pretreatment procedures, aliquots of methamphetamine spiked or abusers' urine samples were simply acidified, dried under
H Wilhelm et al.
German journal of ophthalmology, 5(3), 168-170 (1996-05-01)
In suspected Horner's syndrome, cocaine eye drops are applied to verify the diagnosis. Subsequent application of hydroxyamphetamine or pholedrine eye drops allows localization of the site of the interruption in the oculosympathetic pathway. In the present study the influence of
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