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934135

Sigma-Aldrich

TissueFab® Sodium Persulfate Solution

low endotoxin

Synonym(s):

Sodium persulfate, SPS, SPS Crosslinker, Sodium peroxodisulfate

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About This Item

Linear Formula:
Na2S2O8
CAS Number:
7775-27-1
Molecular Weight:
238.10
MDL number:
MFCD00003501
UNSPSC Code:
12352300
NACRES:
NA.21

Quality Level

100

storage temp.

2-8°C

SMILES string

[Na+].[Na+].[O-]S(=O)(=O)OOS([O-])(=O)=O

InChI

1S/2Na.H2O8S2/c;;1-9(2,3)7-8-10(4,5)6/h;;(H,1,2,3)(H,4,5,6)/q2*+1;/p-2

InChI key

CHQMHPLRPQMAMX-UHFFFAOYSA-L

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General description

Rutheneum (Ru) and sodium persulfate (SPS) have the ability to effectively generate free radicals in the 400-450nm visible light range, allowing for cell-friendly photo-crosslinking of a variety of hydrogels. Among the materials that can be crosslinked via this method are the natturally derived and biocompatible biomaterials silk fibroin and gelatin . These materials can be used to enhance the mechanical and rheological properties to aid the 3D bioprinting workflow.

Application

Sodium persulfate is provided at an optimized concentration for 3D bioprinting applications. It can be used to bioprint via extrusion based 3D bioprinting cell-laden hydrogels in desired shapes and without any supporting materials. Crosslinking of the 3D printed structures is done in one step using visible light. The crosslinked cell-laden bioinks can be further culutred and use for tissue engineering and regenerative medicina applications.
Low Endotoxin, low bioburden: Endotoxins have been demonstrated negatively impact cellular growth, morphology, differentiation, inflammation and protein expression. Bioburden is defined as the number of contaminated organisms found in a given amount of material. We test each lot for endotoxins as well as total bioburden (aerobic and fungal) to minimize unwanted interactions. For more information: https://www.sigmaaldrich.com/US/en/technical-documents/technical-article/microbiological-testing/pyrogen-testing/what-is-endotoxin

Legal Information

Tissuefab is a registered trademark of Sigma-Aldrich Co. LLC
TISSUEFAB is a registered trademark of Merck KGaA, Darmstadt, Germany

Pictograms

Flame over circleHealth hazard
GHS03,GHS08

Signal Word

Danger

Hazard Statements

H272,H317,H334

Hazard Classifications

Ox. Liq. 3 - Resp. Sens. 1 - Skin Sens. 1

Storage Class Code

5.1B - Oxidizing hazardous materials

WGK

nwg

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

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Certificates of Analysis (COA)

Lot/Batch Number
MKCV4180

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Khoon S Lim et al.
Macromolecular bioscience, 19(6), e1900098-e1900098 (2019-04-27)
In this study, the cyto-compatibility and cellular functionality of cell-laden gelatin-methacryloyl (Gel-MA) hydrogels fabricated using a set of photo-initiators which absorb in 400-450 nm of the visible light range are investigated. Gel-MA hydrogels cross-linked using ruthenium (Ru) and sodium persulfate
Soon Hee Kim et al.
Nature communications, 9(1), 1620-1620 (2018-04-26)
Although three-dimensional (3D) bioprinting technology has gained much attention in the field of tissue engineering, there are still several significant engineering challenges to overcome, including lack of bioink with biocompatibility and printability. Here, we show a bioink created from silk

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