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130532

Sigma-Aldrich

5,7-Dichloro-8-hydroxy-2-methylquinoline

98%

Synonym(s):

5,7-Dichloro-2-methyl-8-quinolinol, 5,7-Dichloro-8-hydroxyquinaldine, 5,7-Dichloro-8-quinaldinol, BCM

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About This Item

Empirical Formula (Hill Notation):
C10H7Cl2NO
CAS Number:
72-80-0
Molecular Weight:
228.07
Beilstein:
156683
EC Number:
200-789-3
MDL number:
MFCD00023984
UNSPSC Code:
12352100
PubChem Substance ID:
24847966
NACRES:
NA.22

Assay

98%

mp

108-112 °C (dec.) (lit.)

SMILES string

Cc1ccc2c(Cl)cc(Cl)c(O)c2n1

InChI

1S/C10H7Cl2NO/c1-5-2-3-6-7(11)4-8(12)10(14)9(6)13-5/h2-4,14H,1H3

InChI key

GPTXWRGISTZRIO-UHFFFAOYSA-N

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Pictograms

Exclamation mark
GHS07

Signal Word

Warning

Hazard Statements

H302

Precautionary Statements

P301 + P312 + P330

Hazard Classifications

Acute Tox. 4 Oral

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

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[Therapeutic efficacy of the combination of chlorquinaldol plus promestriene in infections of the vagina].
S Palacios Gil-Antuñano
Revista clinica espanola, 173(5-6), 297-300 (1984-06-15)
Cutaneous drug reaction case reports: from the world literature.
American journal of clinical dermatology, 3(1), 63-69 (2002-01-31)
Contact cross-sensitization among quinolines.
A Rodríguez et al.
Allergy, 56(8), 795-795 (2001-08-08)
Tzu-Shean Feng et al.
Biochemical pharmacology, 82(3), 236-247 (2011-05-21)
4-Aminoquinolines were hybridized with artemisinin and 1,4-naphthoquinone derivatives via the Ugi-four-component condensation reaction, and their biological activities investigated. The artemisinin-containing compounds 6a-c and its salt 6c-citrate were the most active target compounds in the antiplasmodial assays. However, despite the potent
A Dimitrova et al.
Akusherstvo i ginekologiia, 46(1), 46-47 (2007-05-02)
The data of 30 nonpregnant women in reproductive age BV treated with Gynalgin were presented. On clinical and microbiological indicator Gynalgin showed a good effect on BV-associated microorganisms (80%). Only one of the cases of BV was not affected (4%).
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