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SML3676

Sigma-Aldrich

Midecamycin

≥90% (HPLC)

Synonym(s):

Antibiotic SF 837, SF-837

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About This Item

Empirical Formula (Hill Notation):
C41H67NO15
CAS Number:
35457-80-8
Molecular Weight:
813.97
UNSPSC Code:
51284704
NACRES:
NA.21

Quality Level

100

Assay

≥90% (HPLC)

form

powder

color

white to beige

solubility

DMSO: 2 mg/mL, clear

storage temp.

-10 to -25°C

SMILES string

O=CC[C@H]1C[C@@H](C)[C@@H](O)/C=C/C=C/C[C@@H](C)OC(C[C@@H](OC(CC)=O)[C@@H]([C@H]1O[C@@H]2[C@@H](O)[C@H](N(C)C)[C@@H](O[C@@H]3C[C@]([C@@H](OC(CC)=O)[C@@H](C)O3)(C)O)[C@H](C)O2)OC)=O

Biochem/physiol Actions

Midecamycin is an orally available, broad spectrum macrolide antibiotic produced by Streptomyces mycarofaciens that targets bacterial the 50S ribosomal subunit.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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T Yoshida et al.
The Japanese journal of antibiotics, 35(6), 1462-1474 (1982-06-01)
In vitro midecamycin acetate was shown to have broad spectrum of antibacterial activities similar to those of other macrolides (midecamycin, josamycin, 9-propionyl josamycin and 2'-ethylsuccinyl erythromycin), which include Gram-positive organisms, a part of Gram-negative organisms and anaerobes. Metabolites of midecamycin
[Splenic contraction in patients with various disorders].
A Iio et al.
Kaku igaku. The Japanese journal of nuclear medicine, 23(3), 259-266 (1986-03-01)
Reut Fallek et al.
The Journal of organic chemistry, 87(15), 9688-9698 (2022-07-09)
Seeking to improve the site selectivity of acylation of amphiphilic diols, which is induced by imidazole-based nucleophilic catalysts and directs the reaction toward apolar sites, as we recently reported, we examined a new improved catalytic design and an alteration of

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