SAB4502482

Anti-PTGER3 antibody produced in rabbit

affinity isolated antibody

• Synonym(s): EP3 subtype, PGE receptor, PGE2-R, Prostaglandin E2 receptor EP3 subtype, Prostanoid EP3 receptor
• UNSPSC Code: 12352203
• NACRES: NA.41

Properties

• biological source: rabbit
• Quality Level: 100
• conjugate: unconjugated
• antibody form: affinity isolated antibody
• antibody product type: primary antibodies
• clone: polyclonal
• form: buffered aqueous solution
• mol wt: antigen 43 kDa
• species reactivity: human
• concentration: ~1 mg/mL
• technique(s): ELISA: 1:10000; immunofluorescence: 1:100-1:500
• NCBI accession no.: P43115
• UniProt accession no.: P43115
• shipped in: wet ice
• storage temp.: −20°C
• target post-translational modification: unmodified
• Gene Information: human ... PTGER3(5733)

Description

General description

The PTGER3 (prostaglandin E receptor 3) gene is mapped to human chromosome 1p31.1 and encodes a Gαi coupled receptor protein. It is predominantly localized to the brain in the neurons and activated glial cells. Anti-PTGER3 antibody detects endogenous levels of total PTGER3 protein.

Immunogen

The antiserum was produced against synthesized peptide derived from human PTGER3.

Immunogen Range: 16-65

Biochem/physiol Actions

Prostaglandin E receptor 3 (PTGER3) serves as a receptor for prostaglandin (PG) E1 and E2, to carry out a number of physiological processes. PTGER3 specifically functions to reduce adenylyl cyclase action. It is involved in the activation of the Ras signaling pathway.

Features and Benefits

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Physical form

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Safety Information

• Storage Class Code: 10 - Combustible liquids
• WGK: nwg
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable