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M5266

Sigma-Aldrich

Meglumine diatrizoate

organic

Synonym(s):

N-Methyl-D-glucamine diatrizoate

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About This Item

Empirical Formula (Hill Notation):
C7H17NO5 · C11H9I3N2O4
CAS Number:
131-49-7
Molecular Weight:
809.13
EC Number:
205-024-7
MDL number:
MFCD00069632
UNSPSC Code:
12352201
PubChem Substance ID:
24896990
NACRES:
NA.25

biological source

synthetic (organic)

Quality Level

200

form

powder

optical activity

[α]25/D -6.4 to -5.7 °, c = 1% (w/v) in water

SMILES string

CNC[C@H](O)[C@@H](O)[C@H](O)[C@H](O)CO.CC(=O)Nc1c(I)c(NC(C)=O)c(I)c(C(O)=O)c1I

InChI

1S/C11H9I3N2O4.C7H17NO5/c1-3(17)15-9-6(12)5(11(19)20)7(13)10(8(9)14)16-4(2)18;1-8-2-4(10)6(12)7(13)5(11)3-9/h1-2H3,(H,15,17)(H,16,18)(H,19,20);4-13H,2-3H2,1H3/t;4-,5+,6+,7+/m.0/s1

InChI key

MIKKOBKEXMRYFQ-WZTVWXICSA-N

General description

Meglumine Diatrizoate is an organic, iodinated meglumine salt form of diatrizoate. It is also known as N-Methyl-D-glucamine diatrizoate.

Application

Meglumine diatrizoate can be used to treat long-term Taenia saginata infection. It has also been used to tag fecal matter and bodily fluids in a study investigating preoperative examination techniques in patients with acute colon obstruction caused by colorectal cancer.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Shoji Hirasaki et al.
Internal medicine (Tokyo, Japan), 51(2), 177-179 (2012-01-17)
A 46-year-old Japanese man visited our hospital for chronic abdominal pain, persistent diarrhea and discharge of proglottids for 7 years. He had been living in Lao People's Democratic Republic. Ileography using meglumine/diatrizoate sodium (Gastrografin) revealed a long tapeworm. A Taenia
Cheng Tien Wu et al.
Toxicology and applied pharmacology, 266(1), 167-175 (2012-11-03)
Contrast medium (CM) induces a direct toxic effect on renal tubular cells. This toxic effect subjects in the disorder of CM-induced nephropathy. Our previous work has demonstrated that CM shows to activate the endoplasmic reticulum (ER)-related adaptive unfolding protein response
Patrick Veit-Haibach et al.
European radiology, 23(1), 163-173 (2012-07-10)
Computed tomography perfusion (CTP) can provide information about angiogenesis and blood-flow characteristics in tumours. [18F]Fluoro-2-deoxy-D-glucose-positron emission tomography/computed tomography (FDG-PET/CT) is one of the major oncological imaging techniques which provides information about viability of the tumour cell and partly also about
Nicolas C Buchs et al.
Swiss medical weekly, 142, w13556-w13556 (2012-04-07)
In most centers, Upper Gastrointestinal series (UGI) following Roux-en-Y Gastric Bypass (RYGB) is performed to rule out GJ anastomotic leak. According to the introduction of robotic technology associated with a hypothetical decrease of anastomotic complications, we aim to assess the
B Dustin Pooler et al.
Radiology, 268(1), 127-134 (2013-03-02)
To assess the variation in diagnostic performance among radiologists at screening computed tomographic (CT) colonography. In this HIPAA-compliant, institutional review board-approved study, 6866 asymptomatic adults underwent first-time CT colonographic screening at a single center between January 2005 and November 2011.
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