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Key Documents

G9916

SAFC

EX-CELL® GTM-3

Animal-component free, liquid, sterile-filtered, suitable for cell culture

Pharma Manufacturing

Synonym(s):

Gene Therapy Medium-3 for Adenovirus Production

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About This Item

UNSPSC Code:
12352207
NACRES:
NA.75

Quality Level

description

for research or for further manufacturing use

sterility

sterile-filtered

form

liquid

technique(s)

cell culture | mammalian: suitable

impurities

endotoxin, tested

components

glucose: 2.93 g/L

shipped in

ambient

storage temp.

2-8°C

Features and Benefits

Complete, ready-to-use medium that requires only the addition of L-glutamine for the growth of HEK-293 cells, retinoblastoma-like cells and propagation of adenoviruses. Additionally, the medium is designed to support growth of cells in suspension culture with minimal levels of cell clumping. Developed to meet the needs of biotechnology and vaccine manufacturing.

Caution

Do not freeze.

Reconstitution

Prior to use medium should be warmed to 37°C and supplemented with 20ml/L of 200mM L-glutamine.

Legal Information

EX-CELL is a registered trademark of Merck KGaA, Darmstadt, Germany

Storage Class Code

10 - Combustible liquids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Marina Berdichevsky et al.
Biotechnology progress, 24(1), 158-165 (2007-12-07)
PER.C6 cells, an industrially relevant cell line for adenovirus manufacture, were extensively passaged in serum-free suspension cell culture to better adapt them to process conditions. The changes in cell physiology that occurred during this passaging were characterized by investigating cell

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