A0887

5α-Androstane

• Synonym(s): Etioallocholane
• Empirical Formula (Hill Notation): C₁₉H₃₂
• CAS Number: 438-22-2
• Molecular Weight: 260.46
• NACRES: NA.77
• PubChem Substance ID: 24890466
• UNSPSC Code: 12352211
• EC Number: 207-116-2
• MDL number: MFCD00067600
• Form: powder
• Assay: ≥99% (HPLC)

Properties

• assay: ≥99% (HPLC)
• Quality Segment: 200
• form: powder
• solubility: chloroform: 49-51 mg/mL, clear, colorless
• shipped in: ambient
• storage temp.: room temp
• SMILES string: [H][C@@]12CC[C@@]3([H])CCCC[C@]3(C)[C@@]1([H])CC[C@]4(C)CCC[C@@]24[H]
• InChI: 1S/C19H32/c1-18-11-5-7-16(18)15-9-8-14-6-3-4-12-19(14,2)17(15)10-13-18/h14-17H,3-13H2,1-2H3/t14-,15+,16+,17+,18+,19+/m1/s1
• InChI key: QZLYKIGBANMMBK-UGCZWRCOSA-N
• Gene Information: human ... UGT1A4(54657)

Description

Application

5α-Androstane has been used to treat androgen-dependent and androgen-independent prostate cancer cells (LNCaP and PC-3) to investigate cell proliferation, viability, adhesion and hormone expression.

Other Notes

Serves as the parent steroid skeleton for all androgens, but the hydrocarbon itself is not naturally occurring.

Safety Information

• Storage Class: 11 - Combustible Solids
• wgk: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: Eyeshields, Gloves, type N95 (US)