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86329

Sigma-Aldrich

Taurine

≥99.5% (T), suitable for UHPLC, BioUltra

Synonym(s):

2-Aminoethanesulfonic acid

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About This Item

Linear Formula:
NH2CH2CH2SO3H
CAS Number:
Molecular Weight:
125.15
Beilstein:
1751215
EC Number:
MDL number:
UNSPSC Code:
12352106
PubChem Substance ID:
NACRES:
NA.26

product name

Taurine, BioUltra, ≥99.5% (T)

product line

BioUltra

Quality Level

Assay

≥99.5% (T)

form

powder or crystals

technique(s)

UHPLC: suitable

impurities

insoluble matter, passes filter test

ign. residue (900 °C)

≤0.05%

color

colorless

pH

4.5-6.0 (25 °C, 0.5 M in H2O)

mp

>300 °C (lit.)

solubility

H2O: 0.5 M at 20 °C, clear, colorless

anion traces

chloride (Cl-): ≤50 mg/kg
sulfate (SO42-): ≤500 mg/kg

cation traces

Al: ≤5 mg/kg
As: ≤0.1 mg/kg
Ba: ≤5 mg/kg
Bi: ≤5 mg/kg
Ca: ≤10 mg/kg
Cd: ≤5 mg/kg
Co: ≤5 mg/kg
Cr: ≤5 mg/kg
Cu: ≤5 mg/kg
Fe: ≤5 mg/kg
K: ≤50 mg/kg
Li: ≤5 mg/kg
Mg: ≤5 mg/kg
Mn: ≤5 mg/kg
Mo: ≤5 mg/kg
Na: ≤200 mg/kg
Ni: ≤5 mg/kg
Pb: ≤5 mg/kg
Sr: ≤5 mg/kg
Zn: ≤5 mg/kg

λ

0.5 M in H2O

UV absorption

λ: 260 nm Amax: 0.006
λ: 280 nm Amax: 0.005

application(s)

cell analysis

SMILES string

NCCS(O)(=O)=O

InChI

1S/C2H7NO3S/c3-1-2-7(4,5)6/h1-3H2,(H,4,5,6)

InChI key

XOAAWQZATWQOTB-UHFFFAOYSA-N

Gene Information

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Biochem/physiol Actions

Non-selective endogenous agonist at glycine receptors. Conditionally essential sulfonated amino acid which modulates apoptosis in some cells; functions in many metabolic activities; a product of methionine and cysteine metabolism.

Other Notes

Biological role of taurine; Component of NCTC medium

Storage Class Code

13 - Non Combustible Solids

WGK

WGK 2

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Taurine: biological update.
C E Wright et al.
Annual review of biochemistry, 55, 427-453 (1986-01-01)
CHEMICALLY DEFINED MEDIA FOR CULTIVATION OF LONG-TERM CELL STRAINS FROM FOUR MAMMALIAN SPECIES.
V J EVANS et al.
Experimental cell research, 36, 439-474 (1964-12-01)
Marlene Wewalka et al.
The Journal of clinical endocrinology and metabolism, 99(4), 1442-1451 (2014-01-18)
Bile acids (BAs) are newly recognized signaling molecules in glucose and energy homeostasis. Differences in BA profiles with type 2 diabetes mellitus (T2D) remain incompletely understood. The objective of the study was to assess serum BA composition in impaired glucose-tolerant
Tsutomu Suzuki et al.
Wiley interdisciplinary reviews. RNA, 2(3), 376-386 (2011-10-01)
Mitochondrial DNA mutations that cause mitochondrial dysfunction are responsible for a wide spectrum of human diseases, referred to as mitochondrial diseases. Pathogenic point mutations are found frequently in genes encoding mitochondrial (mt) tRNAs, indicating that impaired functioning of mutant mt
Felizia K Voss et al.
Science (New York, N.Y.), 344(6184), 634-638 (2014-05-03)
Regulation of cell volume is critical for many cellular and organismal functions, yet the molecular identity of a key player, the volume-regulated anion channel VRAC, has remained unknown. A genome-wide small interfering RNA screen in mammalian cells identified LRRC8A as

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