Skip to Content
Merck
All Photos(1)

Key Documents

View All Documentation

52649

Sigma-Aldrich

Hexamethylene diisocyanate

puriss., ≥99.0% (GC)

Synonym(s):

1,6-Diisocyanatohexane

Sign Into View Organizational & Contract Pricing
All Photos(1)

About This Item

Linear Formula:
OCN(CH2)6NCO
CAS Number:
822-06-0
Molecular Weight:
168.19
Beilstein:
956709
EC Number:
212-485-8
MDL number:
MFCD00002047
UNSPSC Code:
12352118
PubChem Substance ID:
57651377
NACRES:
NA.25

grade

puriss.

Quality Level

200

Assay

≥99.0% (GC)

refractive index

n20/D 1.453

bp

82-85 °C/0.1 mmHg

density

1.047 g/mL at 20 °C (lit.)
1.047 g/mL at 20 °C

SMILES string

O=C=NCCCCCCN=C=O

InChI

1S/C8H12N2O2/c11-7-9-5-3-1-2-4-6-10-8-12/h1-6H2

InChI key

RRAMGCGOFNQTLD-UHFFFAOYSA-N

Looking for similar products? Visit Product Comparison Guide

Application

Bifunctional reagent

Signal Word

Danger

Hazard Classifications

Acute Tox. 1 Inhalation - Acute Tox. 4 Oral - Eye Dam. 1 - Resp. Sens. 1 - Skin Corr. 1C - Skin Sens. 1 - STOT SE 3

Target Organs

Respiratory system

Storage Class Code

6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

WGK

WGK 1

Flash Point(F)

266.0 °F - Pensky-Martens closed cup

Flash Point(C)

130 °C - Pensky-Martens closed cup

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number
BCCL9318
BCCH1261
BCBZ8006
BCBR6254V
BCBD4369V

Don't see the Right Version?

If you require a particular version, you can look up a specific certificate by the Lot or Batch number.

Search for a COA

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

G Bieler et al.
Occupational medicine (Oxford, England), 61(6), 440-442 (2011-08-10)
Occupational diisocyanate-induced extrinsic allergic alveolitis (EAA) is a rare and probably underestimated diagnosis. Two acute occupational EAA cases have been described in this context, but neither of them concerned hexamethylene diisocyanate (HDI) exposure. To investigate the cause of a life-threatening
M Janko et al.
American Industrial Hygiene Association journal, 53(5), 331-338 (1992-05-01)
Monitoring of exposure to 1,6-hexamethylene (HDI) monomers and HDI polyisocyanates in Oregon was initiated in 1980 and covered primarily spray painting and related activities. A total of 562 air samples were collected from 60 workplaces during the years 1980-1990 and
Victoria Arrandale et al.
International archives of occupational and environmental health, 86(2), 167-175 (2012-03-14)
Despite the importance of skin exposure, studies of skin symptoms in relation to exposure and respiratory symptoms are rare. The goals of this study were to describe exposure-response relationships for skin symptoms, and to investigate associations between skin and respiratory
Ying-Yu Chen et al.
Langmuir : the ACS journal of surfaces and colloids, 29(11), 3721-3729 (2013-02-28)
The purpose of this study is to develop an injectable thermoresponsive hydrogel system that can undergo sol-gel phase transition by the stimulation of body temperature with improved mechanical stability and biocompatibility as a controlled drug delivery carrier for cancer therapy.
Coralie F Daussy et al.
Journal of virology, 95(3) (2020-11-20)
Hepatitis C virus (HCV) infection triggers Golgi fragmentation through the Golgi-resident protein immunity-related GTPase M (IRGM). Here, we report the roles of NLRP3 (NOD-, LRR- and pyrin domain-containing protein 3) and ASC (apoptosis-associated speck-like protein containing a caspase activation and
View All Related Papers

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service