39303
[6]-Shogaol
analytical standard
Synonym(s):
1-(4-Hydroxy-3-methoxyphenyl)-4-decen-3-one
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About This Item
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grade
analytical standard
Quality Level
Assay
≥90.0% (HPLC)
shelf life
limited shelf life, expiry date on the label
technique(s)
HPLC: suitable
gas chromatography (GC): suitable
application(s)
food and beverages
format
neat
storage temp.
2-8°C
SMILES string
CCCCC\C=C\C(=O)CCc1ccc(O)c(OC)c1
InChI
1S/C17H24O3/c1-3-4-5-6-7-8-15(18)11-9-14-10-12-16(19)17(13-14)20-2/h7-8,10,12-13,19H,3-6,9,11H2,1-2H3/b8-7+
InChI key
OQWKEEOHDMUXEO-BQYQJAHWSA-N
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General description
[6]-Shogaol is a pungent and one of the most abundant dehydrated form of gingerols present in the fresh ginger roots or dried and thermally treated roots. It may serve as a potential anti-inflammatory agent.
Application
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.
Packaging
Bottomless glass bottle. Contents are inside inserted fused cone.
Other Notes
This compound is commonly found in plants of the genus: zingiber
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Pharmacokinetics of 6-gingerol, 8-gingerol, 10-gingerol, and 6-shogaol and conjugate metabolites in healthy human subjects
Cancer Epidemiology, Biomarkers & Prevention, 17, 1930-1936 (2008)
Talanta, 103, 28-32 (2012-12-04)
A new method using reversed phase capillary liquid chromatography was developed for simultaneous determination of four bioactive compounds found in ginger (Zingiber officinale) namely, 6-, 8-, 10-gingerol, and 6-shogaol. The separation of these four compounds was performed using C30 as
Apoptosis : an international journal on programmed cell death, 16(8), 856-867 (2011-05-21)
Shogaols have been previously reported to induce cancer cell death via multiple mechanisms, among which one analog 6-shogaol has been reported to cause microtubule damage through specific reaction with sulfhydryl groups in tubulin. In this study, a series of shogaols
Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 37(14), 2076-2078 (2012-11-07)
To discuss the synergistic mechanism of compatible use of two medicinal herbs, Zingiber offiicinale and Aconitum cainichaeli, by determining single decoction of Z. offiicinale and four gingerols (6-gingerol, 8-gingerol, 6-shogaol, 10-gingerol) contained in compound decoction of Z. offiicinale and A.
Drug metabolism and disposition: the biological fate of chemicals, 40(4), 742-753 (2012-01-17)
Ginger has received extensive attention because of its antioxidant, anti-inflammatory, and antitumor activities. However, the metabolic fate of its major components is still unclear. In the present study, the metabolism of [6]-shogaol, one of the major active components in ginger
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