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8.55047

Sigma-Aldrich

NovaPEG Rink Amide resin

Novabiochem®

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About This Item

UNSPSC Code:
12352111

Quality Level

product line

NovaPEG
Novabiochem®

form

beads

reaction suitability

reaction type: Fmoc solid-phase peptide synthesis

manufacturer/tradename

Novabiochem®

application(s)

peptide synthesis

functional group

amine

storage temp.

2-8°C

General description

An excellent acid-labile resin for the continuous flow and batch Fmoc SPPS of peptide amides. This resin is prepared by derivatization of NovaPEG amino resin with the modified Rink linker. The support has excellent swelling properties in a wide range of solvents, including water, MeCN, MeOH, DCM, DMF, THF, and toluene. In comparative studies this resin was found to give better results than polystyrene-based supports in the synthesis of hydrophobic peptides. The high hydrophilicity was also found to benefit on-resin immunoassays with one-bead-one-peptide libraries [1].

Associated Protocols and Technical Articles
Protocols for Loading of Peptide Synthesis Resins

Linkage

Replaces: 01-64-0473

Analysis Note

Colour (visual): white to light yellow to beige
Appearance of substance (visual): beads
Loading (determined from the substitution of the Fmoc-Leu loaded resin): 0.30 - 0.60 mmol/g
TNBS-Test: passes test
Swelling Volume (in DMF): lot specific result
PEG based resin; 35 - 100 mesh

Legal Information

Novabiochem is a registered trademark of Merck KGaA, Darmstadt, Germany

Storage Class Code

11 - Combustible Solids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Articles

Novabiochem® offers a wide range of linkers and derivatized resins for Fmoc solid-phase peptide synthesis with specialized protocols.

Novabiochem® offers a wide range of linkers and derivatized resins for Fmoc solid-phase peptide synthesis with specialized protocols.

Novabiochem® offers a wide range of linkers and derivatized resins for Fmoc solid-phase peptide synthesis with specialized protocols.

Novabiochem® offers a wide range of linkers and derivatized resins for Fmoc solid-phase peptide synthesis with specialized protocols.

Protocols

Review various resins like Merrifield, trityl-based, and hydroxymethyl-functionalized for peptide immobilization for diverse applications.

Review various resins like Merrifield, trityl-based, and hydroxymethyl-functionalized for peptide immobilization for diverse applications.

Review various resins like Merrifield, trityl-based, and hydroxymethyl-functionalized for peptide immobilization for diverse applications.

Review various resins like Merrifield, trityl-based, and hydroxymethyl-functionalized for peptide immobilization for diverse applications.

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