07-1813

Anti-Septin-2 Antibody

serum, from rabbit

• Synonym(s): Neural precursor cell expressed developmentally down-regulated protein 5, neural precursor cell expressed, developmentally down-regulated 5, septin 2
• UNSPSC Code: 12352203
• eCl@ss: 32160702
• NACRES: NA.41

Properties

• biological source: rabbit
• Quality Level: 100
• antibody form: serum
• antibody product type: primary antibodies
• clone: polyclonal
• species reactivity: rat, human, mouse
• technique(s): immunofluorescence: suitable; western blot: suitable
• NCBI accession no.: NP_004395.1
• UniProt accession no.: Q15019
• shipped in: wet ice
• target post-translational modification: unmodified
• Gene Information: human ... SEPTIN2(4735)

Description

General description

Septin-2 belongs to the septin family of GTPases. Originally characterized as regulators of cytokinesis, septins were later implicated in other cellular processes. Recent studies show that septins have a broader role in microtubule-dependent processes, such as karyokinesis, exocytosis, and maintenance of cell shape. Many members of the septin family have been shown to colocalize or interact with the microtubule cytoskeleton, suggesting that these might be general properties of septins. Septin-2 is expressed in the brain and may be associated with Alzheimer′s disease.

Specificity

This antibody recognizes Septin-2.

Immunogen

Epitope: Unknown

His-tagged recombinant protein corresponding to human Septin-2.

Application

Immunofluorescence: Reported by external laboratory using representative lot.

Research Category
Epigenetics & Nuclear Function

Research Sub Category
Cell Cycle, DNA Replication & Repair

Cell Cycle, DNA Replication & Repair

Use Anti-Septin-2 Antibody (Rabbit Polyclonal Antibody) validated in WB, IF to detect Septin-2 also known as Neural precursor cell expressed developmentally down-regulated protein 5, septin 2.

Quality

Evaluated by Western Blot in Hek293 cell lysate.

Western Blot Analysis: 1:1,000 dilution of this antibody detected Septin-2 on 10 µg of Hek293 cell lysate.

Target description

41 kDa

Physical form

Unpurified

Unpurified rabbit polyclonal with 0.05% sodium azide.

Storage and Stability

Stable for 1 year at -20°C from date of receipt.
Handling Recommendations: Upon receipt and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance.

Analysis Note

Control
Hek293 cell lysate

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Safety Information

• Storage Class Code: 10 - Combustible liquids
• WGK: WGK 1