999984P
Avanti
4ME 16:0 Diether PC
Avanti Research™ - A Croda Brand 999984P, powder
Synonym(s):
1,2-di-O-phytanyl-sn-glycero-3-phosphocholine
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About This Item
Empirical Formula (Hill Notation):
C48H100NO6P
CAS Number:
Molecular Weight:
818.28
UNSPSC Code:
12352211
NACRES:
NA.25
Recommended Products
form
powder
packaging
pkg of 1 × 10 mg (999984P-10mg)
manufacturer/tradename
Avanti Research™ - A Croda Brand 999984P
lipid type
phospholipids
shipped in
dry ice
storage temp.
−20°C
SMILES string
[O-]P(OCC[N+](C)(C)C)(OC[C@]([H])(OCCC(C)CCCC(C)CCCC(C)CCCC(C)C)COCCC(C)CCCC(C)CCCC(C)CCCC(C)C)=O
General description
4ME 16:0 Diether PC or 1,2-di-O-phytanyl-sn-glycero-3-phosphocholine is an archaeal phospholipid having two phytane chains attached to the sn-1 and sn-2 positions of the glycerol backbone by ether bonds. It has choline as the alcohol moiety, attached to the phosphate group.
Application
4ME 16:0 Diether PC or 1,2-di-O-phytanyl-sn-glycero-3-phosphocholine is suitable for the preparation of multilamellar and giant lipid vesicles. It has also been used as a standard to analyze and compare the archaeal abundances in microbial communities based on the phosphoether lipids (PEL) concentrations.
Biochem/physiol Actions
Ether lipids are components of membrane structure, influencing the fluidity and fusion of biological membranes. They possess antioxidative action and helps reducing oxidative stress. Cell differentiation and cellular signalling are some of the other physiological processes controlled by ether lipids.
Packaging
5 mL Clear Glass Sealed Ampule (999984P-10mg)
Legal Information
Avanti Research is a trademark of Avanti Polar Lipids, LLC
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Certificates of Analysis (COA)
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Marta Salvador-Castell et al.
Biochimica et biophysica acta. Biomembranes, 1862(2), 183130-183130 (2019-11-18)
It is now well established that cell membranes are much more than a barrier that separate the cytoplasm from the outside world. Regarding membrane's lipids and their self-assembling, the system is highly complex, for example, the cell membrane needs to
ZhangFei Su et al.
Langmuir : the ACS journal of surfaces and colloids, 34(21), 6249-6260 (2018-05-04)
The insertion and ion-conducting channel properties of alamethicin reconstituted into a 1,2-di- O-phytanyl- sn-glycero-3-phosphocholine bilayer floating on the surface of a gold (111) electrode modified with a 1-thio-β-d-glucose (β-Tg) self-assembled monolayer were investigated using a combination of electrochemical impedance spectroscopy
S A Carr et al.
Geobiology, 11(4), 377-395 (2013-05-21)
Marine sediments of the Ross Sea, Antarctica, harbor microbial communities that play a significant role in the decomposition, mineralization, and recycling of organic carbon (OC). In this study, the cell densities within a 153-cm sediment core from the Ross Sea
Vid Šuštar et al.
PloS one, 7(7), e39401-e39401 (2012-07-14)
As variance from standard phospholipids of eubacteria and eukaryotes, archaebacterial diether phospholipids contain branched alcohol chains (phytanol) linked to glycerol exclusively with ether bonds. Giant vesicles (GVs) constituted of different species of archaebacterial diether phospholipids and glycolipids (archaeosomes) were prepared
John M Dean et al.
Protein & cell, 9(2), 196-206 (2017-05-20)
Ether lipids, such as plasmalogens, are peroxisome-derived glycerophospholipids in which the hydrocarbon chain at the sn-1 position of the glycerol backbone is attached by an ether bond, as opposed to an ester bond in the more common diacyl phospholipids. This
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