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Supelco

3,3′-Dichlorobenzidine solution

certified reference material, 2000 μg/mL in methanol

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About This Item

Empirical Formula (Hill Notation):
C12H10Cl2N2
CAS Number:
91-94-1
Molecular Weight:
253.13
UNSPSC Code:
12000000

grade

certified reference material
TraceCERT®

product line

TraceCERT®

CofA

current certificate can be downloaded

feature

standard type calibration

packaging

ampule of 1 mL

concentration

2000 μg/mL in methanol

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

application(s)

cleaning products
cosmetics
environmental
food and beverages
personal care

format

single component solution

storage temp.

2-8°C

InChI

1S/C12H10Cl2N2/c13-9-5-7(1-3-11(9)15)8-2-4-12(16)10(14)6-8/h1-6H,15-16H2

InChI key

HUWXDEQWWKGHRV-UHFFFAOYSA-N

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General description

3,3′-Dichlorobenzidine is a persistent hydrophobic organic contaminant, found to be carcinogenic in nature and is released into the environment as an intermediate from dye manufacturing processes.

Application

3,3′-Dichlorobenzidine may be used as a certified reference standard for the quantification of the analyte and its congeners in environmental samples using high-performance liquid chromatography technique.
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Other Notes

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

Legal Information

TraceCERT is a registered trademark of Merck KGaA, Darmstadt, Germany

Signal Word

Danger

Hazard Classifications

Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Aquatic Chronic 3 - Carc. 1B - Flam. Liq. 2 - STOT SE 1

Target Organs

Eyes

WGK

WGK 3

Flash Point(F)

closed cup

Flash Point(C)

closed cup

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Certificates of Analysis (COA)

Lot/Batch Number
LRAD9124
LRAD2085
LRAC2116
XA16234V
XA16193V

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Jin-Heon Lee et al.
Industrial health, 41(3), 242-248 (2003-08-15)
3,3'-dichlorobenzidine (DCB) is suspected to be arcinogenic in experimental animal and human. Several studies have investigated excretion of metabolites in urine, hemoglobin adduction and cancer incidence among workers exposed occupationally to DCB. In these researches, metabolites of DCB had a
Kristian F Knoell et al.
Journal of toxicology and environmental health. Part A, 75(8-10), 551-556 (2012-06-13)
In a chemical plant in Germany producing 3,3'-dichlorobenzidine dihydrochloride for the manufacture of colorants, blood and urine samples were taken for biological monitoring. 3,3'-Dichlorobenzidine (DBZ) was analyzed in urine by thin-layer chromatography and subsequently further combined with analysis of adducts
3,3'-Dichlorobenzidine and 3,3'-dichlorobenzidine dihydrochloride.
Report on carcinogens : carcinogen profiles, 11, III87-III89 (2004-01-01)
3,3'-Dichlorobenzidine and 3,3'-dichlorobenzidine dihydrochloride.
Report on carcinogens : carcinogen profiles, 10, 85-87 (2004-08-25)
Takeshi Ohe et al.
Mutation research, 655(1-2), 28-35 (2008-07-19)
3,3'-Dichlorobenzidine (DCB), which has been assigned as a possible carcinogen to humans (Group 2B) by IARC, is produced as a raw material in the manufacture of polymers and dye intermediates. In our previous paper, we identified DCB as an indirect-acting
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