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47868
D-Biotin
analytical standard
Synonym(s):
Biotin, D-Biotin, Bios II, Coenzyme R, Vitamin B7, Vitamin H
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About This Item
Empirical Formula (Hill Notation):
C10H16N2O3S
CAS Number:
Molecular Weight:
244.31
Beilstein:
86838
EC Number:
MDL number:
UNSPSC Code:
12164500
PubChem Substance ID:
Pricing and availability is not currently available.
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grade
analytical standard
feature
standard type water soluble vitamin
packaging
ampule of 100 mg
technique(s)
HPLC: suitable
gas chromatography (GC): suitable
mp
231-233 °C (lit.)
application(s)
pharmaceutical (small molecule)
vitamins, nutraceuticals, and natural products
format
neat
storage temp.
2-8°C
SMILES string
[H][C@]12CS[C@@H](CCCCC(O)=O)[C@@]1([H])NC(=O)N2
InChI
1S/C10H16N2O3S/c13-8(14)4-2-1-3-7-9-6(5-16-7)11-10(15)12-9/h6-7,9H,1-5H2,(H,13,14)(H2,11,12,15)/t6-,7-,9-/m0/s1
InChI key
YBJHBAHKTGYVGT-ZKWXMUAHSA-N
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General description
D-biotin is water soluble vitamin, which belongs to the B-complex group of vitamins.[1] It generally serves as a covalently-bound coenzyme for several carboxylases[1]. It is an essential micronutrient required for normal cell functions and can be obtained both dietary sources as well as gut microbiota.[2]
Application
D-Biotin may be used as an analytical reference standard for the quantification of the analyte in food samples using high-performance liquid chromatography (HPLC)/avidin-binding assay.[3]
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.
Storage Class Code
11 - Combustible Solids
WGK
WGK 1
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
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What is the Department of Transportation shipping information for this product?
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How do I solubilize Product 47868, D-Biotin?
1 answer-
Per the chemicals encyclopedia published by the Royal Society of Chemistry, 13th ed, biotin is readily soluble in hot water or dilute alkali; it is insoluble in other common organic solvents. In our labs, the basic solutions may be Trizma base, 2M ammonium hydroxide, or 1N sodium hydroxide. You can put the biotin into water, and titrate it with base until it goes into solution.
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Is Product 47868, D-Biotin, suitable for cell culture?
1 answer-
Product 47868 D-Biotin, is not cell culture tested, and you should not consider it for cell culture use. The Supelco biotin is a chemical standard to be used in chromatographic methods. For cell culture, consider either the animal cell culture tested biotin (Product No. B4639), or the plant cell culture tested biotin (Product No. B3399).
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What column do you recommend for the analysis of water soluble vitamins, including Biotin?
1 answer-
The Discovery C18 and Ascentis RP-Amide HPLC columns have been used for the separation of ten water soluble vitamins: Ascorbic acid, Biotin, Cyanocobalamin, Folic acid, Niacin, Niacinamide, Pantothenic acid, Pyridoxine, Riboflavin, and Thiamine. Contact Supelco Technical Service for details -- [email protected]
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