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T2141

Sigma-Aldrich

L-Tyrosine 7-amido-4-methylcoumarin

≥98% (TLC), powder

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About This Item

Empirical Formula (Hill Notation):
C19H18N2O4
CAS Number:
94099-57-7
Molecular Weight:
338.36
MDL number:
MFCD00057306
UNSPSC Code:
12352204
PubChem Substance ID:
24900016
NACRES:
NA.83

product name

L-Tyrosine 7-amido-4-methylcoumarin,

Assay

≥98% (TLC)

form

powder

solubility

80% acetic acid: 50 mg/mL, clear to slightly hazy, faintly yellow

storage temp.

−20°C

SMILES string

CC1=CC(=O)Oc2cc(NC(=O)[C@@H](N)Cc3ccc(O)cc3)ccc12

InChI

1S/C19H18N2O4/c1-11-8-18(23)25-17-10-13(4-7-15(11)17)21-19(24)16(20)9-12-2-5-14(22)6-3-12/h2-8,10,16,22H,9,20H2,1H3,(H,21,24)/t16-/m0/s1

InChI key

NRGJYQDVMUOJLU-INIZCTEOSA-N

Packaging

Bottomless glass bottle. Contents are inside inserted fused cone.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Dilip Chandu et al.
Microbiology (Reading, England), 149(Pt 12), 3437-3447 (2003-12-10)
PepN and its homologues are involved in the ATP-independent steps (downstream processing) during cytosolic protein degradation. To obtain insights into the contribution of PepN to the peptidase activity in Escherichia coli, the hydrolysis of a selection of endopeptidase and exopeptidase
B el Moudni et al.
Journal of medical microbiology, 43(4), 282-288 (1995-10-01)
A novel aminopeptidase was purified by high performance liquid chromatography from a cytosoluble 100,000 g extract of Candida albicans on the basis of its ability to cleave L-arginine 7-amino-4-methylcoumarin. The purification factor was 36 and the yield was 20%. The
Rory E Morty et al.
The Journal of biological chemistry, 277(29), 26057-26065 (2002-05-15)
Aminopeptidases are emerging as exciting novel drug targets and vaccine candidates in parasitic infections. In this study, we describe for the first time an aminopeptidase from three highly pathogenic Leishmania species. Intronless genes encoding a leucyl aminopeptidase (lap) were cloned
Karolina Michalska et al.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 29(9), 4071-4079 (2015-06-13)
Marine sediments host a large population of diverse, heterotrophic, uncultured microorganisms with unknown physiologies that control carbon flow through organic matter decomposition. Recently, single-cell genomics uncovered new key players in these processes, such as the miscellaneous crenarchaeotal group. These widespread

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