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SAB5200083

Sigma-Aldrich

Anti-SOD1 antibody produced in rabbit

1 mg/mL, affinity isolated antibody

Synonym(s):

Anti-ALS1, Anti-Cu/Zn SOD, rat, Anti-IPOA, Anti-SOD1, Anti-SOD2, Anti-Superoxide dismutase1

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About This Item

UNSPSC Code:
12352203
NACRES:
NA.41

biological source

rabbit

Quality Level

100

conjugate

unconjugated

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

form

buffered aqueous glycerol solution

mol wt

antigen predicted mol wt 23 kDa

species reactivity

mouse, human, rat, bovine

concentration

1 mg/mL

technique(s)

immunohistochemistry: suitable
immunoprecipitation (IP): suitable
indirect ELISA: suitable
western blot: suitable

NCBI accession no.

NP_058746.1

UniProt accession no.

P00441

shipped in

wet ice

storage temp.

−20°C

target post-translational modification

unmodified

Gene Information

rat ... SOD1(24786)

Related Categories

General description

Superoxide dismutase 1 (SOD1) acts as an anti-oxidant. The gene ID of the protein is 24786.

Specificity

Detects a ~23 kDa (human) and 19 kDa (other species) proteins corresponding to the molecular mass of Cu/Zn superoxide dismutase (SOD) on SDS PAGE immunoblots.

Immunogen

Rat Cu/Zn SOD

Biochem/physiol Actions

Superoxide dismutase 1 (SOD1) offers protection to cells against reactive oxygen species.

Features and Benefits

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

Physical form

PBS, pH 7..0, 50% glycerol, 0.09% sodium azide

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class Code

10 - Combustible liquids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Jong Whi Kim et al.
Journal of veterinary science, 16(1), 11-16 (2014-10-09)
In the present study, we investigated the effects of treadmill exercise on lipid peroxidation and Cu,Zn-superoxide dismutase (SOD1) levels in the hippocampus of Zucker diabetic fatty (ZDF) rats and lean control rats (ZLC) during the onset of diabetes. At 7
Brianna Hnath et al.
Biophysical journal, 121(11), 2084-2095 (2022-05-05)
Accumulation of insoluble amyloid fibrils is widely studied as a critical factor in the pathology of multiple neurodegenerative diseases, including amyotrophic lateral sclerosis (ALS), a fatal neurodegenerative disease. Misfolded Cu, Zn superoxide dismutase (SOD1) was the first protein linked to
Renata Andrade Ávila et al.
Experimental physiology, 106(8), 1772-1784 (2021-06-21)
What is the central question of this study? The current literature indicates that oxidative stress plays a major role in iron overload. Although exercise is a well-established approach to treat/prevent cardiovascular diseases, its effects on iron overload are not known.
Abhirami K Iyer et al.
PloS one, 18(11), e0294731-e0294731 (2023-11-28)
Astrocyte-specific ion pump α2-Na+/K+-ATPase plays a critical role in the pathogenesis of amyotrophic lateral sclerosis (ALS). Here, we test the effect of Atp1a2 mRNA-specific antisense oligonucleotides (ASOs) to induce α2-Na+/K+-ATPase knockdown in the widely used ALS animal model, SOD1*G93A mice.
Yi Yang et al.
Chemical biology & drug design, 99(6), 884-896 (2022-03-22)
Alzheimer's disease (AD) is a chronic neurodegenerative disorder that can cause cognitive impairment. Ginsenoside Rg1 (Rg1) has a significant neuroprotective effect on animals with memory impairment. However, the mechanism of how Rg1 mediates the Wnt signaling pathway and improves cognitive
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