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SAB4503020

Sigma-Aldrich

Anti-p53 (Acetyl-Lys386), C-Terminal antibody produced in rabbit

affinity isolated antibody

Synonym(s):

Antigen NY-CO-13, Cellular tumor antigen p53, Phosphoprotein p53, TP53, Tumor suppressor p53

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About This Item

UNSPSC Code:
12352203
NACRES:
NA.41

biological source

rabbit

conjugate

unconjugated

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

form

buffered aqueous solution

mol wt

antigen 43 kDa

species reactivity

human

concentration

~1 mg/mL

technique(s)

ELISA: 1:40000
immunofluorescence: 1:100-1:500
immunohistochemistry: 1:50-1:100

NCBI accession no.

P04637

UniProt accession no.

P04637

shipped in

wet ice

storage temp.

−20°C

target post-translational modification

acetylation (Lys386)

Gene Information

human ... TP53(7157)

General description

Anti-p53 (Acetyl-Lys386) Antibody detects endogenous levels of total p53 (Acetyl-Lys386) protein.

Immunogen

The antiserum was produced against synthesized peptide derived from human p53 around the acetylated site of Lys386.

Immunogen Range: 344-393

Features and Benefits

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

Physical form

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

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Storage Class Code

10 - Combustible liquids

WGK

nwg

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificates of Analysis (COA)

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Articles

p53: DNA Damage Response and Cancer

p53 regulates gene expression, cell cycle control and functions as a tumor suppressor. Inactivation of p53 is closely tied to cancer development.

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