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SAB3501078

Sigma-Aldrich

Anti-TMIGD1 antibody produced in rabbit

affinity isolated antibody

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About This Item

UNSPSC Code:
12352203
NACRES:
NA.41

biological source

rabbit

conjugate

unconjugated

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

form

buffered aqueous solution

mol wt

predicted mol wt 29 kDa

species reactivity

rat, mouse, human

concentration

1 mg/mL

technique(s)

ELISA: suitable
immunoblotting: suitable

NCBI accession no.

UniProt accession no.

shipped in

wet ice

storage temp.

−20°C

target post-translational modification

unmodified

Gene Information

human ... TMIGD1(388364)

General description

TMIGD1 (Transmembrane and immunoglobulin domain containing 1) is a novel adhesion molecule expressed in several organs and tissues, specifically in renal tubular epithelial cells. It is composed of two putative immunoglobulin domains, which mediates self-dimerization.

Immunogen

Antibody was raised against an 18 amino acid peptide near the center of human TMIGD1.

Application

Anti-TMIGD1 antibody produced in rabbit is suitable for immunoblot and ELISA.

Biochem/physiol Actions

TMIGD1 (Transmembrane and immunoglobulin domain containing 1) is involved in various cellular processes such as regulation of cell structure, cell-cell adhesion, and cellular movement. Its extracellular domain stabilizes the cell morphology and cell-cell interaction. TMIGD1 plays an important role in cell survival by protecting it from oxidative cell injury. It protects cells from oxidative and nutrient-deprivation-induced cell injury by stabilizing the transepithelial electric resistance and permeability of renal epithelial cells.

Features and Benefits

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

Linkage

The action of this antibody can be blocked using blocking peptide SBP3501078.

Physical form

Supplied at 1 mg/mL in PBS with 0.02% sodim azide.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Pricing

Storage Class Code

10 - Combustible liquids

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


Certificates of Analysis (COA)

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Emad Arafa et al.
The American journal of pathology, 185(10), 2757-2767 (2015-09-08)
Oxidative damage to renal tubular epithelial cells is a fundamental pathogenic mechanism implicated in both acute kidney injury and chronic kidney diseases. Because epithelial cell survival influences the outcome of acute kidney injury and chronic kidney diseases, identifying its molecular

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