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S8256

Sigma-Aldrich

Serum thymic factor

≥95% (HPLC)

Synonym(s):

FTS, pGlu-Ala-Lys-Ser-Gln-Gly-Gly-Ser-Asn

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About This Item

Empirical Formula (Hill Notation):
C33H54N12O15
CAS Number:
Molecular Weight:
858.85
MDL number:
UNSPSC Code:
12352200

Assay

≥95% (HPLC)

storage temp.

−20°C

SMILES string

C[C@H](NC(=O)[C@@H]1CCC(=O)N1)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCC(N)=O)C(=O)NCC(=O)NCC(=O)N[C@@H](CO)C(=O)N[C@@H](CC(N)=O)C(O)=O


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J M Pleau et al.
The Journal of biological chemistry, 252(22), 8045-8047 (1977-11-25)
The amino acid sequence of a circulating thymic factor (FTS, facteur thymique sérique) isolated from pig serum has been established as less than Glu-Ala-Lys-Ser-Gln-Gly-Gly-Ser-Asn-OH. This sequence was obtained by Edman analysis both on the intact peptide and after tryptic digestion.
Biochemical characterisation of a serum thymic factor.
J Bach et al.
Nature, 266(5597), 55-57 (1977-03-03)
R G Strachan et al.
Journal of medicinal chemistry, 22(5), 586-588 (1979-05-01)
Less than Glu-Ala-Lys-Ser-Gln-Gly-Gly-Ser-Asn, a proposed serum thymic factor, has been synthesized. The protected precursor, less than Glu-Ala-Lys(i-Noc)-ser(Bzl)-Gln-Gly-Gly-Ser(Bzl)-Asn, was prepared by a combination of solid phase and solution methods. The benzyl blocking groups were removed by HF and the i-Noc blocking

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