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R1276

Sigma-Aldrich

Reversin 121

≥97% (HPLC), powder

Synonym(s):

Boc-Asp(Obzl)-Lys(Z)-OtBu

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About This Item

Empirical Formula (Hill Notation):
C34H47N3O9
CAS Number:
174630-04-7
Molecular Weight:
641.75
MDL number:
MFCD03788012
UNSPSC Code:
12161501
PubChem Substance ID:
329823998
NACRES:
NA.47
Pricing and availability is not currently available.

Quality Level

100

Assay

≥97% (HPLC)

form

powder

color

white

mp

200 °C

solubility

DMSO or ethanol: soluble

storage temp.

−20°C

SMILES string

CC(C)(C)OC(=O)N[C@@H](CC(=O)OCc1ccccc1)C(=O)N[C@@H](CCCCNC(=O)OCc2ccccc2)C(=O)OC(C)(C)C

InChI

1S/C34H47N3O9/c1-33(2,3)45-30(40)26(19-13-14-20-35-31(41)44-23-25-17-11-8-12-18-25)36-29(39)27(37-32(42)46-34(4,5)6)21-28(38)43-22-24-15-9-7-10-16-24/h7-12,15-18,26-27H,13-14,19-23H2,1-6H3,(H,35,41)(H,36,39)(H,37,42)/t26-,27-/m0/s1

InChI key

SVNKEDMVAQBLLN-SVBPBHIXSA-N

Gene Information

human ... GRIN2A(2903)
mouse ... GRIN2A(14811)
rat ... GRIN2A(24409)

General description

Reversin 121 is an analog of reversin and a dipeptide derivative.[1]

Application

Reversin 121 has been used to determine the activity of P-glycoprotein in human retinal pigment epithelium.[2]

Biochem/physiol Actions

Peptide chemosensitizer, inhibitor of P-glycoprotein.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Certificates of Analysis (COA)

Lot/Batch Number
110K4705

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Michelle Prudhomme
Advances in Anticancer Agents in Medicinal Chemistry, 1 (2013)
P-glycoprotein expression in human retinal pigment epithelium
Brain GK, et al.
Molecular Vision (2002)

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