PZ0289

PF-06651481-00

≥98% (HPLC)

• Synonym(s): 4-[(3,5-Dichloro-4-methoxyphenyl)amino]-6-methoxy-7-[3-(4-methyl-1-piperazinyl)propoxy]-3-quinolinecarbonitrile, Bosutinib isomer 4, PF-06651481
• Empirical Formula (Hill Notation): C₂₆H₂₉Cl₂N₅O₃
• CAS Number: 1391063-17-4
• Molecular Weight: 530.45
• MDL number: MFCD22418831
• UNSPSC Code: 12352200
• PubChem Substance ID: 329823815
• NACRES: NA.77

Properties

• Quality Level: 100
• Assay: ≥98% (HPLC)
• form: powder
• color: white to beige
• solubility: DMSO: 10 mg/mL, clear (warmed)
• storage temp.: room temp
• SMILES string: CN(CC1)CCN1CCCOC2=C(OC)C=C3C(N=CC(C#N)=C3NC4=CC(Cl)=C(OC)C(Cl)=C4)=C2
• InChI: 1S/C26H29Cl2N5O3/c1-32-6-8-33(9-7-32)5-4-10-36-24-14-22-19(13-23(24)34-2)25(17(15-29)16-30-22)31-18-11-20(27)26(35-3)21(28)12-18/h11-14,16H,4-10H2,1-3H3,(H,30,31)
• InChI key: YCLIWTLPTXAGPQ-UHFFFAOYSA-N

Description

Biochem/physiol Actions

PF-06651481-00 is an isomer of orally available dual Src/Abl kinase inhibitor Bosutinib.

Safety Information

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable