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Key Documents

P1060

Sigma-Aldrich

1,2-Dioleoyl-sn-glycero-3-phospho-L-serine sodium salt

~95%

Synonym(s):

L-α-Phosphatidyl-L-serine, dioleoyl sodium salt

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About This Item

Linear Formula:
C42H77NO10PNa
CAS Number:
Molecular Weight:
810.03
MDL number:
UNSPSC Code:
51191904
PubChem Substance ID:
NACRES:
NA.25
Pricing and availability is not currently available.

biological source

synthetic (organic)

Assay

~95%

form

powder

functional group

phospholipid

lipid type

phosphoglycerides

shipped in

ambient

storage temp.

−20°C

SMILES string

CCCCCCCC\C=C/CCCCCCCC(=O)OC[C@@H](COP(O)(=O)OC[C@H](N)C(O)=O)OC(=O)CCCCCCC\C=C/CCCCCCCC

InChI

1S/C42H78NO10P/c1-3-5-7-9-11-13-15-17-19-21-23-25-27-29-31-33-40(44)50-35-38(36-51-54(48,49)52-37-39(43)42(46)47)53-41(45)34-32-30-28-26-24-22-20-18-16-14-12-10-8-6-4-2/h17-20,38-39H,3-16,21-37,43H2,1-2H3,(H,46,47)(H,48,49)/b19-17-,20-18-/t38-,39-/m0/s1

InChI key

WTBFLCSPLLEDEM-MDZJKYSESA-N

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Ricardo Capone et al.
Biophysical journal, 98(11), 2644-2652 (2010-06-02)
Antimicrobial peptides (AMPs) are an emerging class of antibiotics for controlling health effects of antibiotic-resistant microbial strains. Protegrin-1 (PG-1) is a model antibiotic among beta-sheet AMPs. Antibiotic activity of AMPs involves cell membrane damage, yet their membrane interactions, their 3D
Hélène Bouvrais et al.
Proceedings of the National Academy of Sciences of the United States of America, 109(45), 18442-18446 (2012-10-25)
Interaction between integral membrane proteins and the lipid-bilayer component of biological membranes is expected to mutually influence the proteins and the membrane. We present quantitative evidence of a manifestation of the lipid-protein interactions in liposomal membranes, reconstituted with actively pumping
Navin Gopaldass et al.
The EMBO journal, 36(22), 3274-3291 (2017-10-17)
Sorting, transport, and autophagic degradation of proteins in endosomes and lysosomes, as well as the division of these organelles, depend on scission of membrane-bound tubulo-vesicular carriers. How scission occurs is poorly understood, but family proteins bind these membranes. Here, we
Hongjie An et al.
Biophysical journal, 99(3), 834-844 (2010-08-05)
The effect of cholesterol (CHOL) on the material properties of supported lipid bilayers composed of lipid mixtures that mimic the composition of lipid microdomains was studied by force-volume (FV) imaging under near-physiological conditions. These studies were carried out with lipid
Anton A Polyansky et al.
The journal of physical chemistry. B, 113(4), 1107-1119 (2009-01-08)
Some membrane-active peptides undergo drastic changes of conformation and/or orientation on water-lipid interfaces. Among the most notable examples is penetratin (pAntp), a short cell-penetrating peptide. To delineate the driving forces behind pAntp-membrane interactions, we used, in this series of two

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