H4395
N-Heptyl-5-Chloro-1-Naphthalenesulfonamide
powder
Synonym(s):
Protein kinase C activator, SC-10
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About This Item
Empirical Formula (Hill Notation):
C17H22ClNO2S
CAS Number:
Molecular Weight:
339.88
MDL number:
UNSPSC Code:
12171500
form
powder
color
white
solubility
DMSO: 10 mM
ethanol: soluble
storage temp.
−20°C
SMILES string
CCCCCCCNS(=O)(=O)c1cccc2c(Cl)cccc12
Certificates of Analysis (COA)
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H Nishino et al.
Biochimica et biophysica acta, 889(2), 236-239 (1986-11-28)
N-(6-Phenylhexyl)-5-chloro-1-naphthalenesulfonamide (SC-9) activated Ca2+-activated, phospholipid-dependent protein kinase (protein kinase C). SC-9 acted as a substitute for phosphatidylserine, which is one of the endogenous factors in activating protein kinase C. SC-9 was also effective in regulating the physiological functions at the
M Ito et al.
Biochemistry, 25(15), 4179-4184 (1986-07-29)
Naphthalenesulfonamide derivatives were used to study the mechanism of regulation of Ca2+-dependent smooth muscle myosin light chain phosphorylation catalyzed by Ca2+-activated, phospholipid-dependent protein kinase (protein kinase C) and myosin light chain kinase. Derivatives such as N-(6-phenylhexyl)-5-chloro-1-naphthalenesulfonamide (SC-9), with a hydrophobic
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