C5554
1-(3-Chlorophenyl)piperazine hydrochloride
Synonym(s):
m-CPP
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About This Item
Empirical Formula (Hill Notation):
C10H13ClN2 · xHCl
CAS Number:
Molecular Weight:
196.68 (free base basis)
EC Number:
MDL number:
UNSPSC Code:
12352200
NACRES:
NA.77
Recommended Products
mp
210-214 °C (dec.) (lit.)
SMILES string
Cl.Clc1cccc(c1)N2CCNCC2
InChI
1S/C10H13ClN2.ClH/c11-9-2-1-3-10(8-9)13-6-4-12-5-7-13;/h1-3,8,12H,4-7H2;1H
InChI key
MHXPYWFZULXYHT-UHFFFAOYSA-N
Gene Information
human ... HTR2C(3358)
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Biochem/physiol Actions
5-HT2c serotonin receptor agonist; metabolite of trazodone.
replaced by
Product No.
Description
Pricing
Signal Word
Warning
Hazard Statements
Precautionary Statements
Hazard Classifications
Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
Storage Class Code
13 - Non Combustible Solids
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
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L Steardo et al.
The Journal of pharmacology and experimental therapeutics, 295(1), 266-273 (2000-09-19)
There are some suggestions that, in the pineal gland, serotonin acts not only as a precursor of melatonin but also plays a role in the modulation of the pineal biosynthetic activity. To corroborate this possible neuromodulatory role of 5-hydroxytryptamine (serotonin)
Y Tozawa et al.
Biochemical pharmacology, 58(8), 1329-1334 (1999-09-16)
Isatin, a stress-related biological substance, increases in rat urine in association with elevated catecholamine biosynthesis during stress. The goal of this study was to unravel how the biosynthetic pathway of isatin is related to stress response. The importance of the
S Rotzinger et al.
Drug metabolism and disposition: the biological fate of chemicals, 26(6), 572-575 (1998-06-17)
The metabolism of the antidepressant drug trazodone to its active metabolite, m-chlorophenylpiperazine (mCPP), was studied in vitro using human liver microsomal preparations and cDNA-expressed human cytochrome P450 (P450) enzymes. The kinetics of mCPP formation from trazodone were determined, and three
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