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C0755

Sigma-Aldrich

Conalbumin from chicken egg white

Substantially iron-free

Synonym(s):

Ovotransferrin

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About This Item

CAS Number:
1391-06-6
EC Number:
215-727-0
MDL number:
MFCD00130856
UNSPSC Code:
12352202
NACRES:
NA.25

biological source

chicken egg white

Assay

≥98% (agarose gel electrophoresis)

form

powder

UniProt accession no.

P02789

storage temp.

−20°C

Gene Information

chicken ... TF(396241)

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General description

Conalbumin is an iron-binding protein. It is mainly present in the egg white of hen. It is also termed as ovotransferrin. It is a member of the transferrin iron-binding glycoproteins family. Ovotransferrin is also known an an acute?phase protein (APP)in some organisms. It is the second main protein found in egg white.

Application

Conalbumin from chicken egg white has been used:
  • as ovotransferrin standard in 96?well microplate assay to investigate on ovotransferrin-like activity in the plasma of wild birds
  • to examine its effects on osteoclastogenesis
  • to study its partitioning in aqueous two-phase systems

Biochem/physiol Actions

Conalbumin/ovotransferrin plays a key role in avian natural immunity. It has the ability to prevent bacterial growth and possesses immunomodulatory functions. Ovotransferrin also exhibits antimicrobial and antioxidant activities.

Pictograms

Health hazard
GHS08

Signal Word

Danger

Hazard Statements

H317,H334

Precautionary Statements

P261 - P280 - P342 + P311

Hazard Classifications

Resp. Sens. 1 - Skin Sens. 1

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Siderophores and transferrins
Dertz EA and Raymond KN
ChemInform, 35(49), no-no (2004)
Miriam S Arrell et al.
Electrophoresis, 37(22), 2913-2921 (2016-10-21)
3-(2-furoyl)quinoline-2-carboxaldehyde (FQ) is a sensitive fluorogenic dye, used for derivatization of proteins for SDS-CGE with LIF detection (SDS-CGE-LIF) at silver staining sensitivity (ng/mL). FQ labels proteins at primary amines, found at lysines and N-termini, which vary in number and accessibility
Innate immune responses
Avian Immunology, 121-147 (2014)
Egg White Ovotransferrin Attenuates RANKL-Induced Osteoclastogenesis and Bone Resorption
Shang N and Wu J
Nutrients, 11(9), 2254-2254 (2019)
Long Huang et al.
Bioengineered, 13(1), 12-26 (2021-12-31)
Long non-coding RNAs (lncRNAs) are related to the initiation and progression of tumor and regulate various cellular processes including growth, invasion, migration, and apoptosis. Understanding the roles and mechanisms of lncRNAs in regulating cancer progression is crucial for formulating novel
View All Related Papers

Articles

HPLC Analysis of Protein Standards (1) on BIOshell™ A400 Protein C4

For use as a marker in SDS-PAGE; Albumin from chicken egg white, For use as a marker in SDS-PAGE; L-Lactic Dehydrogenase from rabbit muscle, Type XI, lyophilized powder, 600-1,200 units/mg protein

Chromatograms

application for HPLC

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