68152

Atto 580 Q maleimide

BioReagent, suitable for fluorescence

• MDL number: MFCD07370570
• UNSPSC Code: 12352200
• NACRES: NA.32

Properties

• product line: BioReagent
• Assay: ≥90% (coupling to thiols)
• form: solid
• manufacturer/tradename: ATTO-TEC GmbH
• technique(s): UV/Vis spectroscopy: suitable
• suitability: corresponds for UV test; suitable for fluorescence
• storage temp.: −20°C

Description

Application

Atto 580Q is a new quencher for fluorescence characterized by high molecular absorption (110.000). Atto 580Q is characterized by a high photostability and thermostability. It is moderately hydrophilic, and soluble in polar solvents as DMF or DMSO. Maleimides are well suited for coupling to thiol groups. This is similar to iodacetamides, but maleimides do react more thiol selective. They do not show significant reaction with histidine or methionine. Hydrolysis of maleimides to a mixture of isomeric nonreactive maleamic acids can compete significantly with thiol modification, particularly above pH 8. Maleimides may be used for labeling of amines, which usually requires a higher pH than reaction of maleimides with thiols.

Legal Information

This product is for Research use only. In case of intended commercialization, please contact the IP-holder (ATTO-TEC GmbH, Germany) for licensing.

Safety Information

• Storage Class Code: 13 - Non Combustible Solids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves