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37150

Sigma-Aldrich

3,3′-Diheptylthiacarbocyanine iodide

for fluorescence

Synonym(s):

DiSC7(3)

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About This Item

Empirical Formula (Hill Notation):
C31H41IN2S2
CAS Number:
53213-88-0
Molecular Weight:
632.71
MDL number:
MFCD01863007
UNSPSC Code:
12352200
PubChem Substance ID:
57649706
Pricing and availability is not currently available.

grade

for fluorescence

form

solid

fluorescence

λex 562 nm; λem 575 nm in methanol

suitability

in accordance for fluorescence

SMILES string

[I-].CCCCCCCN1C(\Sc2ccccc12)=C/C=C/c3sc4ccccc4[n+]3CCCCCCC

InChI

1S/C31H41N2S2.HI/c1-3-5-7-9-15-24-32-26-18-11-13-20-28(26)34-30(32)22-17-23-31-33(25-16-10-8-6-4-2)27-19-12-14-21-29(27)35-31;/h11-14,17-23H,3-10,15-16,24-25H2,1-2H3;1H/q+1;/p-1

InChI key

QJIIDBGAPSEKOV-UHFFFAOYSA-M

Application

3,3′-Diheptylthiacarbocyanine iodide [DiSC7(3)], a cyanine dye, may be used similar to 3,3′-dipropylthiadicarbocyanine iodide [DiSC(3)(5)] for membrane potential studies.

Other Notes

Cyanine dye for measuring membrane potential[1]

Storage Class Code

13 - Non Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Certificates of Analysis (COA)

Lot/Batch Number
402639/1

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Studies on the mechanism by which cyanine dyes measure membrane potential in red blood cells and phosphatidylcholine vesicles.
P J Sims et al.
Biochemistry, 13(16), 3315-3330 (1974-07-30)
Jaromír Plášek et al.
Journal of bioenergetics and biomembranes, 44(5), 559-569 (2012-07-20)
The fluorescent dye 3,3'-dipropylthiadicarbocyanine, diS-C(3)(3), is a suitable probe to monitor real changes of plasma membrane potential in yeast cells which are too small for direct membrane potential measurements with microelectrodes. A method presented in this paper makes it possible
R J W Brooijmans et al.
Journal of bacteriology, 189(14), 5203-5209 (2007-05-15)
Lactococcus lactis, a facultative anaerobic lactic acid bacterium, is known to have an increased growth yield when grown aerobically in the presence of heme. We have now established the presence of a functional, proton motive force-generating electron transfer chain (ETC)
Jaeyong Cho et al.
Biochimica et biophysica acta, 1828(3), 1153-1158 (2012-12-25)
Dioscin is a kind of steroidal saponin isolated from the root bark of wild yam Dioscorea nipponica. We investigated the antifungal effect of dioscin against different fungal strains and its antifungal mechanism(s) in Candida albicans cells. Using the propidium iodide
Adam D Pfefferle et al.
Disease models & mechanisms, 12(7) (2019-06-20)
The Wnt gene family encodes an evolutionarily conserved group of proteins that regulate cell growth, differentiation and stem cell self-renewal. Aberrant Wnt signaling in human breast tumors has been proposed as a driver of tumorigenesis, especially in the basal-like tumor

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