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21902

Sigma-Aldrich

Carboxymethylcellulose sodium salt

medium viscosity

Synonym(s):

Sodium carboxymethylcellulose

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About This Item

CAS Number:
9004-32-4
MDL number:
MFCD00081472
UNSPSC Code:
12352201
NACRES:
NA.25

form

powder

availability

not available in USA

extent of labeling

0.60-0.95 substitution

loss

≤15% loss on drying, 110 °C

color

light yellow

pH

6.5-8.0 (10 mg/mL in H2O)

viscosity

300-1000 mPa.s, 2 % in H2O(25 °C) (dry substance)

mp

> 300.05  °C ((> 572.09 °F ))

InChI

1S/C6H12O6.C2H4O2.Na/c7-1-3(9)5(11)6(12)4(10)2-8;1-2(3)4;/h1,3-6,8-12H,2H2;1H3,(H,3,4);

InChI key

DPXJVFZANSGRMM-UHFFFAOYSA-N

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Application

Soluble carboxymethylcelluloses (CM-cellulose; CMC) available in varying viscosities are used as viscosity modifiers (thickeners) to stabilize emulsions and as a chemical dispersants of oils and other carbon structures such as nanotubes. CMCs are used in the development of biostructures such as biofilms, emulsions and nanoparticles for drug delivery.

Other Notes

To gain a comprehensive understanding of our extensive range of Polysaccharides for your research, we encourage you to visit our Carbohydrates Category page.
Characterization of endoglucanase III from Trichoderma reesei.

Storage Class Code

11 - Combustible Solids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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R Macarrón et al.
The Biochemical journal, 289 ( Pt 3), 867-873 (1993-02-01)
Endoglucanase III (EG III) was purified to homogeneity from the culture medium of Trichoderma reesei QM 9414. It has a molecular mass of 48 kDa, and an isoelectric point of 5.1. Maximal activity was observed between pH4 and 5. Celloligosaccharides
Lihua Cheng et al.
PloS one, 6(9), e25433-e25433 (2011-10-04)
Cisplatin is a potent anticancer drug, but its clinical application has been limited due to its undesirable physicochemical characteristics and severe side effects. Better drug formulations for cisplatin are highly desired. Herein, we have developed a nanoparticle formulation for cisplatin
Georg Geisberger et al.
Small (Weinheim an der Bergstrasse, Germany), 7(19), 2808-2814 (2011-09-29)
Polyoxometalate/carboxymethyl chitosan nanocomposites with an average diameter of 130 nm are synthesized and labeled with fluorescein isothiocyanate (FITC) for a combined drug-carrier and cellular-monitoring approach. [Eu(β(2) -SiW(11) O(39) )(2) ](13-) /CMC nanospheres as a representative example do not display cytotoxicity
Gunnar M Buyse et al.
European heart journal, 30(1), 116-124 (2008-09-12)
Duchenne muscular dystrophy (DMD) is a severe and still incurable disease, with heart failure as a leading cause of death. The identification of a disease-modifying therapy may require early-initiated and long-term administration, but such type of therapeutic trial is not
Michael A Joyce et al.
PLoS pathogens, 15(8), e1007949-e1007949 (2019-08-03)
Host encounters with viruses lead to an innate immune response that must be rapid and broadly targeted but also tightly regulated to avoid the detrimental effects of unregulated interferon expression. Viral stimulation of host negative regulatory mechanisms is an alternate
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