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60356

Sigma-Aldrich

Potassium phosphate dibasic

puriss. p.a., ACS reagent, anhydrous, ≥99.0% (T)

Synonym(s):

Dipotassium hydrogenphosphate, Dipotassium phosphate, sec.-Potassium phosphate

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About This Item

Linear Formula:
K2HPO4
CAS Number:
7758-11-4
Molecular Weight:
174.18
EC Number:
231-834-5
MDL number:
MFCD00011383
UNSPSC Code:
12352302
eCl@ss:
38070212
PubChem Substance ID:
329758898
NACRES:
NB.24

grade

ACS reagent
puriss. p.a.

Assay

≥99.0% (T)

form

powder or crystals

impurities

≤0.001% total nitrogen (N)

loss

≤1.0% loss on drying, 105 °C

pH

8.5-9.6 (25 °C, 50 mg/mL in H2O)

anion traces

chloride (Cl-): ≤30 mg/kg
sulfate (SO42-): ≤50 mg/kg

cation traces

Ca: ≤50 mg/kg
Cd: ≤5 mg/kg
Co: ≤5 mg/kg
Cr: ≤5 mg/kg
Cu: ≤5 mg/kg
Fe: ≤10 mg/kg
Mg: ≤5 mg/kg
Mn: ≤5 mg/kg
Na: ≤500 mg/kg
Ni: ≤5 mg/kg
Pb: ≤5 mg/kg
Zn: ≤5 mg/kg
heavy metals: ≤5 ppm (by ICP-OES)

SMILES string

[K+].[K+].OP([O-])([O-])=O

InChI

1S/2K.H3O4P/c;;1-5(2,3)4/h;;(H3,1,2,3,4)/q2*+1;/p-2

InChI key

ZPWVASYFFYYZEW-UHFFFAOYSA-L

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General description

Potassium phosphate dibasic is a useful biological buffer having a pH in the range of 8.5-9.6. Potassium phosphate is present in various forms: monobasic (KH2PO4), dibasic (KH2PO4), and tribasic (K3PO4). Potassium phosphate buffers are widely employed in equilibrium dialysis, high performance liquid chromatography (HPLC) and affinity capillary electrophoresis studies.

Application


  • beta-lactoglobulin stabilized nanemulsions--Formulation and process factors affecting droplet size and nanoemulsion stability.: This study investigates the impact of formulation and process parameters on the stability and size of beta-lactoglobulin stabilized nanemulsions, potentially involving potassium phosphate dibasic in the formulation process (Ali et al., 2016).

  • Correlation of characteristics of gel extrusion module (GEM) tablet formulation and drug dissolution rate.: Examines how the characteristics of gel extrusion in tablet formulations influence drug dissolution rates, relevant for chemists looking into dissolution behavior and possibly involving potassium phosphate dibasic (Juang and Storey, 2003).

  • High-performance liquid chromatographic determination of phenylureas by photochemically-induced fluorescence detection.: Discusses a method for detecting phenylureas using high-performance liquid chromatography, which could involve potassium phosphate dibasic as a component of the mobile phase or sample preparation (Munoz de la Pena et al., 2002).

  • Assay and purity analysis of diatrizoate sodium in drug product by LC.: This research details a method for assaying and analyzing the purity of diatrizoate sodium, where potassium phosphate dibasic could be part of the chromatographic system (Chellquist et al., 1997).

Storage Class Code

13 - Non Combustible Solids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificates of Analysis (COA)

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H Einarsson et al.
Applied and environmental microbiology, 61(2), 669-676 (1995-02-01)
In brined shrimp (ca. 3% NaCl), the effects of three different lactic acid bacteria bacteriocins (crude [6.54 x 10(sup10) U of bacteriocin activity {BU}/g] and purified [8.13 x 10(sup23) BU/g] nisin Z, carnocin UI49 [2.32 x 10(sup4) BU/g], and crude
Tessy Theres Baby et al.
Talanta, 80(5), 2016-2022 (2010-02-16)
A new type of amperometric glucose biosensor based on silicon dioxide coated magnetic nanoparticle decorated multiwalled carbon nanotubes (Fe(3)O(4)@SiO(2)/MWNTs) on a glassy carbon electrode (GCE) has been developed. MWNTs have been synthesized by catalytic chemical vapour decomposition (CCVD) of acetylene
John E Schiel et al.
Talanta, 65(2), 495-500 (2008-10-31)
Potassium phosphate buffer is often used in methods such as equilibrium dialysis, high performance liquid chromatography (HPLC), and affinity capillary electrophoresis (ACE) for characterizing the binding of drugs and hormones with proteins or other ligands within the body. In these
Dongwon Baek et al.
Plant physiology, 161(1), 362-373 (2012-11-17)
Although a role for microRNA399 (miR399) in plant responses to phosphate (Pi) starvation has been indicated, the regulatory mechanism underlying miR399 gene expression is not clear. Here, we report that AtMYB2 functions as a direct transcriptional activator for miR399 in
Yan Liu et al.
PLoS genetics, 10(1), e1004005-e1004005 (2014-01-28)
Interhomolog recombination plays a critical role in promoting proper meiotic chromosome segregation but a mechanistic understanding of this process is far from complete. In vegetative cells, Rad51 is a highly conserved recombinase that exhibits a preference for repairing double strand
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