P1290000

Phenytoin

European Pharmacopoeia (EP) Reference Standard

• Synonym(s): 5,5-Diphenylhydantoin, 5,5-Diphenyl-2,4-imidazolidinedione, Phenytoin
• Empirical Formula (Hill Notation): C₁₅H₁₂N₂O₂
• CAS Number: 57-41-0
• Molecular Weight: 252.27
• Beilstein: 384532
• MDL number: MFCD00005264
• UNSPSC Code: 41116107
• PubChem Substance ID: 329820085
• NACRES: NA.24

Properties

• grade: pharmaceutical primary standard
• API family: phenytoin
• manufacturer/tradename: EDQM
• technique(s): HPLC: suitable; gas chromatography (GC): suitable
• mp: 293-295 °C (lit.)
• application(s): pharmaceutical (small molecule)
• format: neat
• SMILES string: O=C1NC(=O)C(N1)(c2ccccc2)c3ccccc3
• InChI: 1S/C15H12N2O2/c18-13-15(17-14(19)16-13,11-7-3-1-4-8-11)12-9-5-2-6-10-12/h1-10H,(H2,16,17,18,19)
• InChI key: CXOFVDLJLONNDW-UHFFFAOYSA-N
• Gene Information: human ... SCN10A(6336) , SCN11A(11280) , SCN1A(6323) , SCN2A(6326) , SCN3A(6328) , SCN4A(6329) , SCN5A(6331) , SCN7A(6332) , SCN8A(6334) , SCN9A(6335)

Description

General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the Issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Phenytoin EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

Biochem/physiol Actions

Reduces incidence of grand mal seizures; appears to stabilize excitable membranes perhaps through effects on Na⁺, K⁺, and Ca²⁺ channels.

Packaging

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Other Notes

Sales restrictions may apply.

Safety Information

• Pictograms: GHS08,GHS07
• Signal Word: Danger
• Hazard Statements: H302,H351,H360FD
• Precautionary Statements: P202 - P264 - P270 - P280 - P301 + P312 - P308 + P313
• Hazard Classifications: Acute Tox. 4 Oral - Carc. 2 - Repr. 1B
• Storage Class Code: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• WGK: WGK 3