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68459

Supelco

Ethosuximide

analytical standard

Synonym(s):

2-Ethyl-2-methylsuccinimide

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About This Item

Empirical Formula (Hill Notation):
C7H11NO2
CAS Number:
77-67-8
Molecular Weight:
141.17
EC Number:
201-048-7
MDL number:
MFCD00072123
UNSPSC Code:
41116107
PubChem Substance ID:
329760914
NACRES:
NA.24
Pricing and availability is not currently available.

grade

analytical standard

Quality Level

100

Assay

≥98.0% (GC)

shelf life

limited shelf life, expiry date on the label

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

application(s)

forensics and toxicology
pharmaceutical (small molecule)
veterinary

format

neat

SMILES string

O=C1NC(CC1(C)CC)=O

InChI

1S/C7H11NO2/c1-3-7(2)4-5(9)8-6(7)10/h3-4H2,1-2H3,(H,8,9,10)

InChI key

HAPOVYFOVVWLRS-UHFFFAOYSA-N

Gene Information

human ... CACNA1G(8913) , CACNA1H(8912) , CACNA1I(8911)

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Application

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Pictograms

Exclamation mark
GHS07

Signal Word

Warning

Hazard Statements

H302

Hazard Classifications

Acute Tox. 4 Oral

Storage Class Code

13 - Non Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

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Certificates of Analysis (COA)

Lot/Batch Number
BCCC9526
BCBT7551

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S J Wallace
Epilepsy research, 29(2), 147-154 (1998-02-26)
Based on small numbers of patients, it is possible to make the following suggestions rather than categorical statements. For myoclonic seizures and epilepsies which are not otherwise specified, valproate seems of proven efficacy. Ethosuximide may be a useful adjunct. The
[Ethosuximide].
M Ichiba et al.
Nihon rinsho. Japanese journal of clinical medicine, 53 Su Pt 1, 915-917 (1995-02-01)
J S Millership et al.
European journal of drug metabolism and pharmacokinetics, 18(4), 349-353 (1993-10-01)
The metabolism of the antiepileptic drug ethosuximide (3-ethyl-3-methylpyrollidine-2,5-dione) (I) in animals and humans is reviewed. Chiral aspects of the metabolism of ethosuximide are discussed. Clarification of the precise nature of the hydroxymetabolites of ethosuximide is presented.
Sloka S Iyengar et al.
Experimental neurology, 264, 135-149 (2014-12-06)
Adult neurogenesis, the generation of new neurons in the adult brain, occurs in the hippocampal dentate gyrus (DG) and the olfactory bulb (OB) of all mammals, but the functions of these new neurons are not entirely clear. Originally, adult-born neurons
G V Massey et al.
Pediatric neurology, 11(1), 59-61 (1994-07-01)
We describe a case of aplastic anemia in an 8-year-old girl which was diagnosed 8 months after initiation of ethosuximide as treatment for absence seizures. Blood counts had been previously monitored and were normal. The patient successfully underwent allogeneic bone
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