CHAPS-RO

CHAPS

98% (from N), suitable for dialysis, solubility: >50% (Aqueous solutions)

• Synonym(s): 3-[(3-Cholamidopropyl)dimethylammonio]-1-propanesulfonate hydrate, 3-[(3-cholamidopropyl)dimethyl-ammonio]-1-propane sulfonate, 3-[(3-cholamidopropyl)dimethyl-ammonio]-1-propane sulfonate, zwitterionic, Cholamidopropyl-dimethyl-ammonio]-1-propane sulfonate, 3-3-, zwitterionic, cholamidopropyl-dimethyl-ammonio]-1-propane sulfonate, 3-3-, CHAPS
• Empirical Formula (Hill Notation): C₃₂H₅₈N₂O₇S · xH₂O
• CAS Number: 331717-45-4
• Molecular Weight: 614.88 (anhydrous basis)
• MDL number: MFCD00012116
• UNSPSC Code: 12161900

Properties

• description: zwitterionic
• Assay: 98% (from N)
• form: crystals
• mol wt: 614.88 g/mol (anhydrous basis)
• packaging: pkg of 10 g (10810118001); pkg of 50 g (10810126001)
• manufacturer/tradename: Roche
• technique(s): dialysis: suitable
• CMC: 4 mM
• mp: 157 °C (dec.) (lit.)
• solubility: >50% (Aqueous solutions)
• absorption: <0.06% at 278 nm in water at 1 % (w/v) (Ease of removal*: ++; Note:; * Arbitrary scale ranges from ++ to −)
• storage temp.: 2-8°C
• SMILES string: O.C[C@H](CCC(=O)NCCC[N+](C)(C)CCCS([O-])(=O)=O)[C@H]1CC[C@H]2[C@@H]3[C@H](O)C[C@@H]4C[C@H](O)CC[C@]4(C)[C@H]3C[C@H](O)[C@]12C
• InChI: 1S/C32H58N2O7S.H2O/c1-21(8-11-29(38)33-14-6-15-34(4,5)16-7-17-42(39,40)41)24-9-10-25-30-26(20-28(37)32(24,25)3)31(2)13-12-23(35)18-22(31)19-27(30)36;/h21-28,30,35-37H,6-20H2,1-5H3,(H-,33,38,39,40,41);1H2/t21-,22+,23-,24-,25+,26+,27-,28+,30+,31+,32-;/m1./s1
• InChI key: SJCUTFKCLFLIFE-JWTJKVBLSA-N

Description

General description

3-[(3-Cholamidopropyl)dimethyl-ammonio]-1-propane sulfonate

Application

Solubilization of membrane proteins. Combines the properties of both the sulfobetaine-type and bile-acid detergents.

Physical form

Crystals

Preparation Note

Working concentration: PAGE: 6.5 to 13 mM
Storage conditions (working solution): Do not store in solution, because precipitation may occur.

Other Notes

For life science research only. Not for use in diagnostic procedures.

Safety Information

• Pictograms: GHS07
• Signal Word: Warning
• Hazard Statements: H302 - H315 - H319
• Precautionary Statements: P264 - P270 - P280 - P301 + P312 + P330 - P337 + P313 - P501
• Hazard Classifications: Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2
• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 1
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable