ABT335

Anti-SYNPO2L Antibody

from rabbit, purified by affinity chromatography

• Synonym(s): Synaptopodin 2-like, cytoskeletal heart-enriched actin-associated protein, CHAP, SYNPO2L
• UNSPSC Code: 12352203
• eCl@ss: 32160702
• NACRES: NA.41

Properties

• biological source: rabbit
• Quality Level: 100
• antibody form: affinity isolated antibody
• antibody product type: primary antibodies
• clone: polyclonal
• purified by: affinity chromatography
• species reactivity: human, mouse
• technique(s): immunofluorescence: suitable; immunohistochemistry: suitable; western blot: suitable
• UniProt accession no.: Q9H987
• shipped in: wet ice
• target post-translational modification: unmodified
• Gene Information: human ... SYNPO2L(79933)

Description

General description

SYNPO2L, also known as Synaptopodin 2-like protein, is a member of the synaptopodin family. SYNPO2L was initially identified as a novel heart-enriched gene that encodes a cytoskeletal protein highly expressed in the Z-disc of heart and skeletal muscle. It has been shown that even though SYNPO2L is primarily localized to the sarcomere, it can also translocate to the nucleus. Recent studies in zebrafish suggest that SYNPO2L may play an important role in muscle development.

Immunogen

KLH-conjugated linear peptide corresponding to human SYNPO2L.

Application

Anti-SYNPO2L Antibody is a highly specific rabbit polyclonal antibody, that targets Synaptopodin 2-like protein & has been tested in western blotting, Immunofluorescence & IHC.

Immunofluorescence Analysis: 5 µg/mL from a representative lot detected SYNPO2L in mouse skeletal muscle cells.

Immunohistochemistry Analysis: A 1:50 dilution from a representative lot detected SYNPO2L in human cardiac myocytes.

Research Category
Cell Structure

Research Sub Category
Cytoskeletal Signaling

Quality

Evaluated by Western Blotting in human thymus tissue lysate.

Western Blotting Analysis: 1µg/mL of this antibody detected SYNPO2L in 15 µg of human thymus tissue lysate.

Target description

~95 kDa observed. Uncharacterized bands may appear in some lysates. Uniprot describes 2 isoforms at ~79 kDa and ~103 kDa

Physical form

Antigen Affinity Purified

Purified rabbit polyclonal in buffer containing PBS with up to 0.1% sodium azide.

Storage and Stability

Stable for 1 year at 2-8°C from date of receipt.

Analysis Note

Control
Human thymus tissue lysate

Other Notes

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Safety Information

• Storage Class Code: 10 - Combustible liquids
• WGK: WGK 2
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable