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AB1056

Sigma-Aldrich

Anti-Adenovirus Antibody

Chemicon®, from goat

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About This Item

UNSPSC Code:
12352203
eCl@ss:
32160702
NACRES:
NA.41

biological source

goat

Quality Level

antibody form

purified antibody

antibody product type

primary antibodies

clone

polyclonal

species reactivity

human

manufacturer/tradename

Chemicon®

technique(s)

ELISA: suitable
immunofluorescence: suitable
immunohistochemistry: suitable
western blot: suitable

shipped in

wet ice

Specificity

Adenovirus, hexon assembly. No cross-reactivity with Para 1-3, Influenza A & B or RSV. Non reactive with HEp-2 cells.

Immunogen

Hexon from adenovirus type 5.

Application

ELISA: >1:5,000

Fluorescence microscopy, indirect.

Immunoblotting: unboiled samples in 1mM DTT and 2% SDS only

Immunohistochemistry

Optimal working dilutions must be determined by end user
Research Category
Infectious Diseases
Research Sub Category
Infectious Diseases - Viral
This Anti-Adenovirus Antibody is validated for use in ELISA, IF, WB, IH for the detection of Adenovirus.

Physical form

Format: Purified
IgG fraction (>95% pure). In PBS (0.01 M, pH 7.2) with 0.1% sodium azide

Storage and Stability

Maintain at -20° in undiluted aliquots for up to 12 months after date of receipt. Avoid repeated freeze/thaw cycles.

Other Notes

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Legal Information

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class Code

12 - Non Combustible Liquids

WGK

WGK 2

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Highly efficient and carcinoma-specific adenoviral replication restricted by the EGP-2 promoter.
W M Gommans, P M J McLaughlin, J A C Schalk, G M M Groothuis, H J Haisma, M G Rots
Journal of Controlled Release : Official Journal of the Controlled Release Society null
M Verónica Lopez et al.
PloS one, 4(4), e5119-e5119 (2009-04-02)
The clinical efficacy of conditionally replicative oncolytic adenoviruses (CRAd) is still limited by the inefficient infection of the tumor mass. Since tumor growth is essentially the result of a continuous cross-talk between malignant and tumor-associated stromal cells, targeting both cell
Matthew Glen Robertson et al.
Molecular therapy oncolytics, 20, 659-668 (2021-04-06)
Encoding the sodium iodide symporter (NIS) by an adenovirus (Ad) is a promising strategy to facilitate non-invasive imaging and radiotherapy of pancreatic cancer. However, insufficient levels of NIS expression in tumor cells have limited its clinical translation. To optimize Ad-based
Lynette M Phillips et al.
Neuro-oncology, 23(11), 1911-1921 (2021-06-02)
Oncolytic adenoviruses are promising new treatments against solid tumors, particularly for glioblastoma (GBM), and preclinical models are required to evaluate the mechanisms of efficacy. However, due to the species selectivity of adenovirus, there is currently no single animal model that
J-W Choi et al.
Gene therapy, 20(9), 880-892 (2013-03-22)
Adenoviruses (Ad) have been investigated for their efficacy in reducing primary tumors after local intratumoral administration. Despite high Ad concentrations and repetitive administration, the therapeutic efficacy of Ad has been limited because of rapid dissemination of the Ad into the

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