Skip to Content
Merck
All Photos(1)

Documents

343333

Sigma-Aldrich

5-Fluoro-2′-deoxyuridine

≥98% (HPLC), solid, anticancer agent, Calbiochem®

Synonym(s):

5-Fluoro-2′-deoxyuridine, FdUrd, FUdR, 5-FdU, Floxuridine

Sign Into View Organizational & Contract Pricing


About This Item

Empirical Formula (Hill Notation):
C9H11FN2O5
CAS Number:
Molecular Weight:
246.19
MDL number:
UNSPSC Code:
12352200
NACRES:
NA.77

product name

5-Fluoro-2′-deoxyuridine, Experimental anticancer agent shown to have activity against a variety of malignant neoplasms, including mouse mammary tumors and colorectal carcinomas.

Quality Level

Assay

≥98% (HPLC)

form

solid

manufacturer/tradename

Calbiochem®

storage condition

OK to freeze

color

white

solubility

aqueous buffer: 1 mg/mL
water: 1 mg/mL

shipped in

ambient

storage temp.

2-8°C

InChI

1S/C9H11FN2O5/c10-4-2-12(9(16)11-8(4)15)7-1-5(14)6(3-13)17-7/h2,5-7,13-14H,1,3H2,(H,11,15,16)/t5-,6+,7+/m0/s1

InChI key

ODKNJVUHOIMIIZ-RRKCRQDMSA-N

General description

Experimental anti-cancer agent shown to have activity against a variety of malignant neoplasms, including mouse mammary tumors and colorectal carcinomas.
Experimental anticancer agent shown to have activity against a variety of malignant neoplasms, including mouse mammary tumors and colorectal carcinomas.

Biochem/physiol Actions

Cell permeable: no
Primary Target
Experimental anticancer agent
Product does not compete with ATP.
Reversible: no

Warning

Toxicity: Toxic & Carcinogenic / Teratogenic (G)

Other Notes

Due to the nature of the Hazardous Materials in this shipment, additional shipping charges may be applied to your order. Certain sizes may be exempt from the additional hazardous materials shipping charges. Please contact your local sales office for more information regarding these charges.
Nakagama, H., et al. 2001. Jpn. J. Clin. Oncol.31, 251.
Malmberg, M., et al. 1993. Cell Prolif. 26, 291.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Pictograms

Skull and crossbones

Signal Word

Danger

Hazard Statements

Hazard Classifications

Acute Tox. 3 Oral

Storage Class Code

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

WGK

WGK 3


Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Customers Also Viewed

Slide 1 of 1

1 of 1

Sheng Xiao et al.
iScience, 24(11), 103263-103263 (2021-11-12)
Recent improvements in genetically encoded voltage indicators enabled optical imaging of action potentials and subthreshold transmembrane voltage in vivo. To perform high-speed voltage imaging of many neurons simultaneously over a large anatomical area, widefield microscopy remains an essential tool. However, the
Inhibition of Chk2 promotes neuroprotection, axon regeneration, and functional recovery after CNS injury.
Taylor, et al.
Science Advances, 8, eabq2611-eabq2611 (2022)
Thanasis Rogdakis et al.
Biomedicines, 10(3) (2022-03-26)
Neurotrophins are growth factors that exert important neuroprotective effects by preventing neuronal death and synaptic loss. Nerve Growth Factor (NGF) acts through the activation of its high-affinity, pro-survival TrkA and low-affinity, pro-apoptotic p75NTR receptors. NGF has been shown to slow

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service