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217503

Sigma-Aldrich

Cardiotoxin

from Naja pallida, ≥95% (HPLC), lyophilized solid, cytolytic toxin, Calbiochem®

Synonym(s):

Cardiotoxin, Naja pallida

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About This Item

CAS Number:
UNSPSC Code:
12352202
NACRES:
NA.32

product name

Cardiotoxin, Naja pallida,

Assay

≥95% (HPLC)

Quality Level

form

lyophilized solid

manufacturer/tradename

Calbiochem®

storage condition

OK to freeze

solubility

water: 1 mg/mL

shipped in

ambient

storage temp.

2-8°C

General description

Cardiotoxins, which are highly basic peptides, interact with negatively charged lipids on membranes. While the presence of Lysine residues is crucial for their activity, cardiotoxins demonstrate varying effects on different cells, indicating selective binding to certain cell types.

Application

Cardiotoxin, Naja pallida has been used:
  • to inject into the TA of the 4-month-old dystrophic mice to address whether ILA treatment could modulate muscle regeneration
  • to induce a skeletal muscle injury into the right TA muscle
  • to induce muscle regeneration

Warning

Toxicity: Harmful (C)

Reconstitution

Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.

Other Notes

Jang, J.Y., et al. 1997. Biochemistry 36, 4635.
Huang, J.L., and Trumble, W.R. 1991. Toxicon29, 31.
Raynor, R.L., et al. 1991. J. Biol. Chem.266, 2753.
Grognet, J.M., et al. 1986. Mol. Immunol.23, 132.

Legal Information

Not available for sale outside of the United States.
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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