1.06386

Sodium carbonate monohydrate

EMPROVE^® ESSENTIAL, Ph. Eur., BP, NF, E 500

• Synonym(s): Sodium carbonate monohydrate, Soda monohydrate, Sodium Carbonate Monohydrate
• Empirical Formula (Hill Notation): CNa₂O₃ · xH₂O
• CAS Number: 5968-11-6
• Molecular Weight: 105.99 (anhydrous basis)
• MDL number: MFCD00149177
• UNSPSC Code: 12352302
• E Number: E500
• EC Index Number: 207-838-8

Properties

• Agency: BP; NF; Ph. Eur.
• Quality Level: 500
• product line: EMPROVE^® ESSENTIAL
• form: solid
• pH: 11-12 (25 °C, 50 g/L in H₂O)
• mp: 854 °C (anhydrous substance)
• density: 2.25 g/cm³ at 20 °C
• application(s): liquid formulation; pharmaceutical; solid formulation
• storage temp.: 2-30°C
• InChI: 1S/CH2O3.2Na.H2O/c2-1(3)4;;;/h(H2,2,3,4);;;1H2/q;2*+1;/p-2
• InChI key: MQRJBSHKWOFOGF-UHFFFAOYSA-L

Description

General description

Finding the right excipient that matches your needs as well as regulatory demands can be a complicated challenge in formulation. With our application know-how and regulatory expertise, we support you in every step of development, scale-up, and production.
As part of our Emprove^® Program, our raw materials are offered with extensive documentation facilitating compliance of your pharma and biopharma product, full supply chain transparency and risk mitigation. Our SAFC^® portfolio of high-quality products for biopharmaceutical and pharmaceutical formulation and production withstands strict quality control procedures and is produced according to applicable cGMP guidelines.

Application

Sodium carbonate is a commonly used ingredient in both food and pharmaceutics. In pharmaceutical applications, sodium carbonate is used as pH adjuster, or a source of carbon dioxide in oral formulations such as effervescent tablets or granules.

Legal Information

Emprove is a registered trademark of Merck KGaA, Darmstadt, Germany

SAFC is a registered trademark of Merck KGaA, Darmstadt, Germany

Safety Information

• Pictograms: GHS07
• Signal Word: Warning
• Hazard Statements: H319
• Precautionary Statements: P264 - P280 - P305 + P351 + P338 - P337 + P313
• Hazard Classifications: Eye Irrit. 2
• Storage Class Code: 13 - Non Combustible Solids
• WGK: WGK 1
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable