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1.01894

Millipore

Brij® 35 solution

(30% w/w in water) for biochemistry

Synonym(s):

Polyoxyethylene (23) Lauryl Ether, Polyoxyethylene lauryl ether, Polyoxyethyleneglycol Dodecyl Ether

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About This Item

UNSPSC Code:
12352401
NACRES:
NA.21

Quality Level

form

liquid

pH

5-7 (20 °C in H2O)

density

1.03 g/cm3 at 20 °C

storage temp.

15-25°C

General description

Brij® 35 is a common nonionic surfactant, which has a dodecyl apolar core and a polyoxyethylene chain-formed polar surface. It comprises several hydrophobic and hydrogen-bonding interaction sites with target analytes. Brij 35 is edible and non-toxic.

Application

Brij® 35 solution has been used to develop a novel hexafluoroisopropanol (HFIP)/Brij-35 supramolecular solvent (SUPRAS)-based liquid-phase microextraction (LPME) of parabens. It has also been used to study the formation of water-in-ionic liquid (w/IL) microemulsions in IL 1-butyl-3-methylimidazolium hexafluorophosphate ([bmim][PF6]).

Biochem/physiol Actions

Brij® 35 is known as the “green” modifier in micellar liquid chromatography due to its capability to simulate the biopartitioning process. It forms water-in-ionic liquid (w/IL) microemulsions with IL 1-butyl-3-methylimidazolium hexafluorophosphate ([bmim][PF6]) in the bulk phase. It can also form reverse micelle-type aggregates inside [bmim][PF6] in the absence of added water.

Analysis Note

Identity (IR-spectrum): conforms
Turbidity: ≤ 2.0 NTU
(equivalent to turbidityclass I according to DAB)

Legal Information

Brij is a registered trademark of Croda International PLC

Pictograms

Exclamation mark

Signal Word

Warning

Hazard Statements

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2

Storage Class Code

12 - Non Combustible Liquids

WGK

WGK 2

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


Certificates of Analysis (COA)

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Rewa Rai et al.
Langmuir : the ACS journal of surfaces and colloids, 30(34), 10156-10160 (2014-08-15)
Brij-35, a common and popular nonionic surfactant, is shown to form water-in-ionic liquid (w/IL) microemulsions with IL 1-butyl-3-methylimidazolium hexafluorophosphate ([bmim][PF6]) as the bulk phase. The presence of w/[bmim][PF6] microemulsions is hinted by the significantly increased solubility of water in Brij-35
Jia Chen et al.
Journal of chromatography. A, 1591, 33-43 (2019-01-21)
A novel supramolecular solvent (SUPRAS) based on hexafluoroisopropanol (HFIP)/Brij-35 was proposed for liquid-phase microextraction (LPME) of parabens in water samples, pharmaceuticals and personal care products. Brij-35 is a cost-effective and non-toxic non-ionic surfactant, but it has a high cloud point

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