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07-806

Sigma-Aldrich

Anti-phospho-c-Kit (Tyr568/Tyr570) Antibody

Upstate®, from rabbit

Synonym(s):

KIT, CD117, PBT, SCFR, v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog

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About This Item

UNSPSC Code:
12352203
eCl@ss:
32160702
NACRES:
NA.41

biological source

rabbit

Quality Level

100

antibody form

affinity purified immunoglobulin

antibody product type

primary antibodies

clone

polyclonal

purified by

affinity chromatography

species reactivity

human

manufacturer/tradename

Upstate®

technique(s)

western blot: suitable

isotype

IgG

NCBI accession no.

NM_000222.2
NM_001093772.1

UniProt accession no.

P10721

shipped in

dry ice

target post-translational modification

phosphorylation (pTyr568/pTyr570)

Gene Information

human ... KIT(3815)

Specificity

Predicted to cross-react with Mouse and Rat based on complete sequence homology.
Recognizes phospho-c-Kit (Tyr568/ Tyr570)

Immunogen

Peptide corresponding to amino acid region encompassing the human, mouse, rat, chicken, cow and dog. phospho-c-Kit (Tyr568/ Tyr570).

Application

Anti-phospho-c-Kit (Tyr568/Tyr570) Antibody is an antibody against phospho-c-Kit (Tyr568/Tyr570) for use in WB.
Research Category
Signaling
Research Sub Category
Growth Factors & Receptors

Quality

Routinely evaluated by immunoblot.

Physical form

ImmunoAffinity Purified

Legal Information

UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class Code

12 - Non Combustible Liquids

WGK

WGK 2

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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D J Price et al.
The Journal of biological chemistry, 272(9), 5915-5920 (1997-02-28)
The Csk homologous kinase (CHK), formerly MATK, has previously been shown to bind to activated c-KIT. In this report, we characterize the binding of SH2(CHK) to specific phosphotyrosine sites on the c-KIT protein sequence. Phosphopeptide inhibition of the in vitro

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