I-009
Ibuprofen solution
1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®
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About This Item
Empirical Formula (Hill Notation):
C13H17O2
CAS Number:
Molecular Weight:
205.27
EC Number:
UNSPSC Code:
41116107
NACRES:
NA.24
Recommended Products
grade
certified reference material
form
liquid
feature
Snap-N-Spike®/Snap-N-Shoot®
packaging
ampule of 1 mL
manufacturer/tradename
Cerilliant®
concentration
1.0 mg/mL in methanol
technique(s)
gas chromatography (GC): suitable
liquid chromatography (LC): suitable
application(s)
clinical testing
format
single component solution
storage temp.
−20°C
SMILES string
CC(C)Cc1ccc(cc1)C(C)C([O-])=O
InChI
1S/C13H18O2/c1-9(2)8-11-4-6-12(7-5-11)10(3)13(14)15/h4-7,9-10H,8H2,1-3H3,(H,14,15)/p-1
InChI key
HEFNNWSXXWATRW-UHFFFAOYSA-M
General description
Ibuprofen is a non-steroidal anti-inflammatory drug (NSAID) used to treat fever, pain, and inflammation. Ibuprofen functions as an unspecific COX inhibitor. This Certified Spiking Solution® is applicable for use in LC/MS or GC/MS applications for clinical toxicology, forensic analysis, or pharmaceutical research.
Application
- Ibuprofen solution in environmental analysis: A study demonstrated the use of green and efficient magnetic micro-solid phase extraction techniques, utilizing tea waste impregnated with magnetic nanoparticles for the analysis of ibuprofen in water samples. This method, enhanced by UV-vis spectrophotometry, showcases the application of ibuprofen solution in monitoring pharmaceutical pollutants, ensuring environmental safety and compliance (Muniandy et al., 2024).
- Pharmacological research with ibuprofen solution: Research into less toxic solvents for in-situ forming PLGA implants incorporated ibuprofen solutions to study drug release profiles. This investigation highlights the role of ibuprofen solution in developing advanced drug delivery systems that are crucial for controlled and sustained medication release, enhancing patient compliance and therapeutic outcomes (Ramos et al., 2024).
- Ibuprofen solution in biomedical applications: A novel study utilized ibuprofen solution to fabricate a green electrospun Janus membrane doped with hierarchical magnesium hydrogen phosphate. This research underlines the utility of ibuprofen in creating advanced materials for the removal of pharmaceuticals from water, contributing to the development of new filtration technologies (Zhu et al., 2024).
- Ibuprofen solution in neuroscience: Researchers quantified the lymphatic transport of model therapeutics from the brain using ibuprofen solutions in rats. This study provides valuable insights into the mechanisms of drug transport in neurological conditions, offering potential pathways for targeted drug delivery to the brain (Hoang et al., 2024).
Legal Information
CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany
CERTIFIED SPIKING SOLUTION is a registered trademark of Cerilliant Corporation
Snap-N-Shoot is a registered trademark of Cerilliant Corporation
Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany
Signal Word
Danger
Hazard Statements
Precautionary Statements
Hazard Classifications
Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1
Target Organs
Eyes,Central nervous system
Storage Class Code
3 - Flammable liquids
WGK
WGK 2
Flash Point(F)
49.5 °F - closed cup
Flash Point(C)
9.7 °C - closed cup
Certificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
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T A Trappe et al.
American journal of physiology. Endocrinology and metabolism, 282(3), E551-E556 (2002-02-08)
We examined the effect of two commonly consumed over-the-counter analgesics, ibuprofen and acetaminophen, on muscle protein synthesis and soreness after high-intensity eccentric resistance exercise. Twenty-four males (25 +/- 3 yr, 180 +/- 6 cm, 81 +/- 6 kg, and 17
K S Albert et al.
The American journal of medicine, 77(1A), 40-46 (1984-07-13)
The pharmacokinetics of ibuprofen (Motrin) are best described by a two-compartment open model. Ibuprofen pharmacokinetics are only minimally influenced by advanced age, the presence of alcoholic liver disease, or rheumatoid arthritis. Levels of ibuprofen in breast milk are negligible. In
J B Whitlam et al.
Clinical pharmacology and therapeutics, 29(4), 487-492 (1981-04-01)
Free and total ibuprofen levels in serum and synovial fluid (SF) were determined in one male and 14 female arthritic patients (mean age 56 yr, range 19 to 77) after 400 mg three times daily for 2 days. Free drug
Sheena Derry et al.
The Cochrane database of systematic reviews, 10(10), CD007550-CD007550 (2013-10-24)
This review is an update of a previously published review in The Cochrane Database of Systematic Reviews Issue 3, 2009 on single dose oral dexibuprofen (S(+)-ibuprofen) for acute postoperative pain in adults.Dexibuprofen is a non-steroidal anti-inflammatory drug (NSAID) licensed for
Massimo Imazio et al.
The New England journal of medicine, 369(16), 1522-1528 (2013-09-03)
Colchicine is effective for the treatment of recurrent pericarditis. However, conclusive data are lacking regarding the use of colchicine during a first attack of acute pericarditis and in the prevention of recurrent symptoms. In a multicenter, double-blind trial, eligible adults
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