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Key Documents

W325201

Sigma-Aldrich

β-Alanine

≥98%, FG

Synonym(s):

β-Ala, 3-Aminopropionic acid

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About This Item

Linear Formula:
NH2CH2CH2COOH
CAS Number:
Molecular Weight:
89.09
FEMA Number:
3252
Beilstein:
906793
EC Number:
MDL number:
UNSPSC Code:
12164502
PubChem Substance ID:
Flavis number:
17.001
NACRES:
NA.21
Organoleptic:
odorless
grade:
FG
Halal
biological source:
synthetic
food allergen:
no known allergens
Pricing and availability is not currently available.

biological source

synthetic

grade

FG
Halal

reg. compliance

EU Regulation 1334/2008 & 872/2012

Assay

≥98%

mp

202 °C (dec.) (lit.)

application(s)

flavors and fragrances

Documentation

see Safety & Documentation for available documents

food allergen

no known allergens

Organoleptic

odorless

SMILES string

NCCC(O)=O

InChI

1S/C3H7NO2/c4-2-1-3(5)6/h1-2,4H2,(H,5,6)

InChI key

UCMIRNVEIXFBKS-UHFFFAOYSA-N

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Biochem/physiol Actions

β-Alanine, a β−amino acid, is a component of pantothenic acid and the rate-limiting amino acid in the biosynthesis of the histidinyl antioxidant dipeptides carnosine and anserine. Endogenous β-amino acid that is a nonselective agonist at glycine receptors and a ligand for the G protein-coupled orphan receptor, TGR7 (MrgD). β-Alanine flux plays a cytoprotective role by supporting the osmotic stability of marine organisms, preimplantation mouse embryos and mammalian cells exposed to hypoxic stress.

Storage Class Code

13 - Non Combustible Solids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Ammar Majeed et al.
Circulation, 128(21), 2325-2332 (2013-10-02)
The aim of this study was to compare the management and prognosis of major bleeding in patients treated with dabigatran or warfarin. Two independent investigators reviewed bleeding reports from 1034 individuals with 1121 major bleeds enrolled in 5 phase III
Robert G Hart et al.
The Canadian journal of cardiology, 29(7 Suppl), S71-S78 (2013-06-29)
Chronic kidney disease (CKD) is prevalent in elderly patients with atrial fibrillation and is an independent risk factor for stroke. Warfarin anticoagulation is efficacious for stroke prevention in atrial fibrillation patients with moderate CKD (stage III, estimated glomerular filtration rate
G D Heggie et al.
Cancer research, 47(8), 2203-2206 (1987-04-15)
Kinetics of 5-fluorouracil (FUra) and FUra metabolites in plasma and urine were investigated in 10 cancer patients following i.v. bolus administration of 500 mg/m2 FUra with 600 microCi of [6-3H]FUra. Biliary excretion was examined in two patients with external biliary
Ramin Artang et al.
The American journal of cardiology, 112(12), 1973-1979 (2013-10-01)
Dabigatran has been associated with greater risk of myocardial infarction (MI) than warfarin. It is unknown whether the increased risk is unique to dabigatran, an adverse effect shared by other oral direct thrombin inhibitors (DTIs), or the result of a
K M Gibson et al.
Journal of neurochemistry, 81(1), 71-79 (2002-06-18)
Metabolite profiling in succinate semialdehyde dehydrogenase (SSADH; Aldh5a1-/-) deficient mice previously revealed elevated gamma-hydroxybutyrate (GHB) and total GABA in urine and total brain and liver extracts. In this study, we extend our metabolic characterization of these mutant mice by documenting

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